Replicative Helicase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Replicative Helicase
  Conformer 1
(PDB) 		2r6c (A)
  Conformer 2
(PDB) 		2r6c (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 221 0.11   183 - 439
2 133 0.18   17 - 149

Sequence


           ________________________________________________________________________________________________________________________ 
 2r6c(A) : EAEQAVLGAVFLDPAALVPASEILIPEDFYRAAHQKIFHAMLRVADRGEPVDLVTVTAELAASEQLEEIGGVSYLSELADAVPTAANVEYYARIVEEKSVLRRLIRTATSIAQDGYTRED 
         :                                                                                                                          
 2r6c(B) : EAEQAVLGAVFLDPAALVPASEILIPEDFYRAAHQKIFHAMLRVADRGEPVDLVTVTAELAASEQLEEIGGVSYLSELADAVPTAANVEYYARIVEEKSVLRRLIRTATSIAQDGYTRED 
           ________________________________________________________________________________________________________________________ 

           ___________148__________________________________________________________________________________________________________ 
 2r6c(A) : EIDVLLDEADRKIMEiTGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNIAQNVATKTNENVAIFSLEMSAQQLVMRMLCAEGNINAQNLRTGKLTPEDWGKLTMAMGSLSNAG 
         :                                                                                                                          
 2r6c(B) : EIDVLLDEADRKIMEiTGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNIAQNVATKTNENVAIFSLEMSAQQLVMRMLCAEGNINAQNLRTGKLTPEDWGKLTMAMGSLSNAG 
           ___________148__________________________________________________________________________________________________________ 

           ______________________________________________________________________________________________________________________   
 2r6c(A) : IYIDDTPSIRVSDIRAKCRRLKQESGLGMIVIDYLQLIQeVSEISRSLKALARELEVPVIALSQLrPMMSDIRESGSIEQDADIVAFLYeIIIAKQRNGPVGTVQLAFIKEYNKFVNL   
         :                                                                                                                          
 2r6c(B) : IYIDDTPSIRVSDIRAKCRRLKQESGLGMIVIDYLQLIQeVSEISRSLKALARELEVPVIALSQLrPMMSDIRESGSIEQDADIVAFLYeIIIAKQRNGPVGTVQLAFIKEYNKFVNL   
           ______________________________________________________________________________________________________________________   

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		99.2
Translation
(A) 		19.2
Closure
(%) 		84.0
Bending Residues
( green ) 		  148 - 184
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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