Serine/threonine-Protein Kinase Pak 6

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Serine/threonine-Protein Kinase Pak 6
  Conformer 1
(PDB) 		2f57 (B)
  Conformer 2
(PDB) 		2cdz (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 201 0.63   497 - 508   526 - 715
2 83 1.4   429 - 496   509 - 525

Sequence


           ___________________________________________________________________________496_________508______________525_____________ 
 2f57(B) : LYFQSMSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHT 
         :                                                                                                                          
 2cdz(A) : ********VSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVR--gKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHT 
           ___________________________________________________________________________368_________380______________397_____________ 

           ________________________________________________________________________________________________________________________ 
 2f57(B) : RMNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKlVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSL 
         :                                                                                                                          
 2cdz(A) : RMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKlVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNL 
           ________________________________________________________________________________________________________________________ 

           ___________________________________________________________                                                              
 2f57(B) : PPRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRH                                                              
         :                                                                                                                          
 2cdz(A) : PPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRT                                                              
           ___________________________________________________________                                                              

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		13.8
Translation
(A) 		0.3
Closure
(%) 		55.5
Bending Residues
( green ) 		  496 - 501
  508 - 509
  525 - 526
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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