Anti-Hiv-1 Antibody 2F5 Light Chain

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Anti-Hiv-1 Antibody 2F5 Light Chain
  Conformer 1
(PDB)
1tjh (L)
  Conformer 2
(PDB)
1u8k (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 104 0.32   106 - 209
2 103 0.31   3 - 105

Sequence


           ______________________________________________________________________________________________________105_______________ 
 1tjh(L) : ALQLTQSPSSLSASVGDRITITCRASQGVTSALAWYRQKPGSPPQLLIYDASSLESGVPSRFSGSGSGTEFTLTISTLRPEDFATYYCQQLHFYPHTFGGGTRVDVRRTVAAPSVFIFPP 
         :                                                                                                                          
 1u8k(A) : ALQLTQSPSSLSASVGDRITITCRASQGVTSALAWYRQKPGSPPQLLIYDASSLESGVPSRFSGSGSGTEFTLTISTLRPEDFATYYCQQLHFYPHTFGGGTRVDVRRTVAAPSVFIFPP 
           ______________________________________________________________________________________________________105_______________ 

           ______________________________________________________________________________________________                           
 1tjh(L) : SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE*                           
         :                                                                                                                          
 1u8k(A) : SDRQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYECEVTHQGLSSPVTKSFNRGEC                           
           ______________________________________________________________________________________________                           

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
4.3
Translation
(A)
0.1
Closure
(%)
84.6
Bending Residues
( green )
  105 - 106
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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