Camp-Dependent Protein Kinase, Alpha-Catalytic Subunit

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Camp-Dependent Protein Kinase, Alpha-Catalytic Subunit
  Conformer 1
(PDB)
1j3h (A)
  Conformer 2
(PDB)
1bkx (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 223 0.6   14 - 32   92 - 104   124 - 316
2 90 0.88   33 - 91   105 - 123   336 - 348

Sequence


           ______________________32_________________________________________________________91_________103_________________123_____ 
 1j3h(A) : GSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEM 
         :                                                                                                                          
 1bkx(A) : ***QESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEM 
           ______________________32_________________________________________________________91_________103_________________123_____ 

           ________________________________________________________________________________________________________________________ 
 1j3h(A) : FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWl-gTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 
         :                                                                                                                          
 1bkx(A) : FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWlCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 
           ________________________________________________________________________________________________________________________ 

           __________________________________________________________310_______________________________________                     
 1j3h(A) : IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKF----------dYEEEEIRViNEKCGKEFTEF                     
         :                                                                                                                          
 1bkx(A) : IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRViNEKCGKEFTEF                     
           __________________________________________________________310_______________________________________                     

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
16.8
Translation
(A)
0.8
Closure
(%)
89.9
Bending Residues
( green )
  32 - 34
  91 - 92
  103 - 105
  123 - 124
  310 - 336
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download