Glutamate Receptor Subunit 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor Subunit 2
  Conformer 1
(PDB) 		1fto (A)
  Conformer 2
(PDB) 		1mqh (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 145 0.49   7 - 109   217 - 258
2 108 0.44   110 - 216   259 - 259

Sequence


           ________________________________________________________________________________________________________109_____________ 
 1fto(A) : **TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
         :                                                                                                                          
 1mqh(A) : NKTVVVTTILESPYVMMKKNHEALEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
           ________________________________________________________________________________________________________109_____________ 

           ___________________________________________________________________________________________216__________________________ 
 1fto(A) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
         :                                                                                                                          
 1mqh(A) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
           ___________________________________________________________________________________________216__________________________ 

           ___________256______                                                                                                     
 1fto(A) : EQGLLDKLKNKWWYDKGEC*                                                                                                     
         :                                                                                                                          
 1mqh(A) : EQGLLDKLKNKWWYDKGECG                                                                                                     
           ___________256______                                                                                                     

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		16.7
Translation
(A) 		-0.5
Closure
(%) 		93.9
Bending Residues
( green ) 		  109 - 110
  216 - 218
  256 - 259
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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