Glutamate Receptor Ionotropic, Nmda 2A

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor Ionotropic, Nmda 2A
  Conformer 1
(PDB) 		4nf5 (B)
  Conformer 2
(PDB) 		4jwx (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 162 0.81   9 - 134   239 - 239   241 - 281
2 107 1.78   135 - 238   240 - 240   282 - 283

Sequence


           ________________________________________________________________________________________________________________________ 
 4nf5(B) : NHLSIVTLEEAPFVIVEDI------cVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVD 
         :                                                                                                                          
 4jwx(A) : NHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVD 
           ________________________________________________________________________________________________________________________ 

           _____134________________________________________________________________________________________________233_____________ 
 4nf5(B) : FSVPFVETGISVMVSRGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYG 
         :                                                                                                                          
 4jwx(A) : FSVPFVETGISVMVSRGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYG 
           _____134________________________________________________________________________________________________233_____________ 

           ________________________________281_____                                                                                 
 4nf5(B) : IALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGICH*                                                                                 
         :                                                                                                                          
 4jwx(A) : IALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGICHA                                                                                 
           ________________________________281_____                                                                                 

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		14.9
Translation
(A) 		0.2
Closure
(%) 		98.8
Bending Residues
( green ) 		  134 - 135
  233 - 242
  281 - 282
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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