DynDom - Protein Domain Motions

Unconventional Myosin-Ib

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Unconventional Myosin-Ib
Conformer 1 (PDB)	6c1g (P)
Conformer 2 (PDB)	6c1d (P)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	606	1.26	8 - 76 80 - 418 433 - 630
2	117	2.16	77 - 79 419 - 432 631 - 730

Sequence

`_____________________________________________________________________76_________________________________________________` `6c1g(P) : VKSSLLDNMIGVGDTVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYV` `:` `6c1d(P) : VKSSLLDNMIGVGDTVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYV` `_____________________________________________________________________76_________________________________________________` `________________________________________________________________________________________________________________________` `6c1g(P) : AAVCGKGAEVNQVKEQLLQSTPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLHKLKLERDFSRYNYLSLDSAKVNGV` `:` `6c1d(P) : AAVCGKGAEVNQVKEQLLQSTPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLHKLKLERDFSRYNYLSLDSAKVNGV` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6c1g(P) : DDAANFRTVRNAMQIVGFSDPEAESVLEVVAAVLKLGNIEFKPESRMNGLDESKIKDKNELKEICELTSIDQVVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLV` `:` `6c1d(P) : DDAANFRTVRNAMQIVGFSDPEAESVLEVVAAVLKLGNIEFKPESRMNGLDESKIKDKNELKEICELTSIDQVVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLV` `________________________________________________________________________________________________________________________` `__________________________________________________418___________432_____________________________________________________` `6c1g(P) : NRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCAT` `:` `6c1d(P) : NRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCAT` `__________________________________________________418___________432_____________________________________________________` `________________________________________________________________________________________________________________________` `6c1g(P) : HQHFESRMSKCSRFLNDTTLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAH` `:` `6c1d(P) : HQHFESRMSKCSRFLNDTTLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAH` `________________________________________________________________________________________________________________________` `___________________627__________________________________________________________________________________________________` `6c1g(P) : IFSESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFL` `:` `6c1d(P) : IFSESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFL` `___________________627__________________________________________________________________________________________________` `_________` `6c1g(P) : LMKGLNDIF` `:` `6c1d(P) : LMKGLNDIF` `_________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	25.1
Translation (A)	0.4
Closure (%)	38.8
Bending Residues ( green )	76 - 80 418 - 419 432 - 433 627 - 631
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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