Unconventional Myosin-Ib

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Unconventional Myosin-Ib
  Conformer 1
(PDB) 		6c1d (P)
  Conformer 2
(PDB) 		6c1h (P)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 538 1.49   13 - 25   31 - 44   46 - 61   73 - 74   81 - 86   90 - 107   127 - 171   181 - 382   384 - 417   434 - 593   596 - 612   619 - 629
2 186 4.8   8 - 12   26 - 30   45 - 45   62 - 72   75 - 80   87 - 89   108 - 126   172 - 180   383 - 383   418 - 433   594 - 595   613 - 618   630 - 731

Sequence


           __8_______________25___30____________44_______________61_________72______80____86_89_______________107________________12 
 6c1d(P) : VKSSLLDNMIGVGDTVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYV 
         :                                                                                                                          
 6c1h(P) : VKSSLLDNMIGVGDTVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVISVNPYRSLPIYSPEKVEDYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYV 
           __8_______________25___30____________44_______________61_________72______80____86_89_______________107________________12 

           6__________________________________________171______180_________________________________________________________________ 
 6c1d(P) : AAVCGKGAEVNQVKEQLLQSTPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLHKLKLERDFSRYNYLSLDSAKVNGV 
         :                                                                                                                          
 6c1h(P) : AAVCGKGAEVNQVKEQLLQSTPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLHKLKLERDFSRYNYLSLDSAKVNGV 
           6__________________________________________171______180_________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 6c1d(P) : DDAANFRTVRNAMQIVGFSDPEAESVLEVVAAVLKLGNIEFKPESRMNGLDESKIKDKNELKEICELTSIDQVVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLV 
         :                                                                                                                          
 6c1h(P) : DDAANFRTVRNAMQIVGFSDPEAESVLEVVAAVLKLGNIEFKPESRMNGLDESKIKDKNELKEICELTSIDQVVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLV 
           ________________________________________________________________________________________________________________________ 

           ______________382________________________________417_____________433____________________________________________________ 
 6c1d(P) : NRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCAT 
         :                                                                                                                          
 6c1h(P) : NRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCAT 
           ______________382________________________________417_____________433____________________________________________________ 

           _________________________________________________________________________________________________________593____________ 
 6c1d(P) : HQHFESRMSKCSRFLNDTTLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAH 
         :                                                                                                                          
 6c1h(P) : HQHFESRMSKCSRFLNDTTLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKAGHALIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAH 
           _________________________________________________________________________________________________________593____________ 

           ____612___618________629________________________________________________________________________________________________ 
 6c1d(P) : IFSESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFL 
         :                                                                                                                          
 6c1h(P) : IFSESLVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFL 
           ____612___618________629________________________________________________________________________________________________ 

           _________                                                                                                                
 6c1d(P) : LMKGLNDIF                                                                                                                
         :                                                                                                                          
 6c1h(P) : LMKGLNDIF                                                                                                                
           _________                                                                                                                

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		11.8
Translation
(A) 		0.4
Closure
(%) 		61.5
Bending Residues
( green ) 		  113 - 116
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

Poly(A) polymerase

PyMOL Script

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