Interferon-Inducible Gtpase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Interferon-Inducible Gtpase
  Conformer 1
(PDB)
1tpz (A)
  Conformer 2
(PDB)
1tqd (B)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 331 0.99   25 - 32   67 - 410
2 42 0.47   17 - 24   33 - 66

Sequence


           _________24______32_______________________________65____________________________________________________________________ 
 1tpz(A) : NDLPSSFTGYFKKFNTGRKIISQEILNLIELRMRKGNIQLTNSAISDALKEIDSSVLNVAVTGETGSGKSSFINTLRGIGNEEEGAAKTGVVEVTMERHPYKHPNIPNVVFWDLPGIGST 
         :                                                                                                                          
 1tqd(B) : NDLPSSFTGYFKKFNTGRKIISQEILNLIELRMRKGNIQLTNSAISDALKEIDSSVLNVAVTGETGSGKSSFINTLRGIGNEEEGAAKT-----tMERHPYKHPNIPNVVFWDLPGI--- 
           _________24______32_______________________________65____________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1tpz(A) : NFPPDTYLEKMKFYEYDFFIIISATRFKKNDIDIAKAISMMKKEFYFVRTKVDSDITNEADkEKVLQDIRLNCVNTFRENGIAEPPIFLLSNKNVCHYDFPVLMDKLISDLPIYKRHNFM 
         :                                                                                                                          
 1tqd(B) : ----dTYLEKMKFYEYDFFIIISATRFKKNDIDIAKAISMMKKEFYFVRTKVDSDITNE--kEKVLQDIRLNCVNTFRENGIAEPPIFLLSNKNVCHYDFPVLMDKLISDLPIYKRHNFM 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1tpz(A) : VSLPNITDSVIEKKRQFLKQRIWLEGFAADLVNIIPSLTFLLDSDLETLKKSMKFYRTVFGVDETSLQRLARDWEIEVDQVEAMIKSPAVFKPTDEETIQERLSRYIQEFCLANGYLLPK 
         :                                                                                                                          
 1tqd(B) : VSLPNITDSVIEKKRQFLKQRIWLEGFAADLVNIIPSLTFLLDSDLETLKKSMKFYRTVFGVDETSLQRLARDWEIEVDQVEAMIKSPAVFKPTDEETIQERLSRYIQEFCLANGYLLPK 
           ________________________________________________________________________________________________________________________ 

           ___________________________________                                                                                      
 1tpz(A) : NSFLKEIFYLKYYFLDMVTEDAKTLLKEICLKLGR                                                                                      
         :                                                                                                                          
 1tqd(B) : NSFLKEIFYLKYYFLDMVTEDAKTLLKEICLRN**                                                                                      
           ___________________________________                                                                                      

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
9.3
Translation
(A)
-0.3
Closure
(%)
73.9
Bending Residues
( green )
  24 - 25
  32 - 33
  65 - 67
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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