Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Metabotropic Glutamate Receptor Subtype 1
  Conformer 1
(PDB)
1ewk (B)
  Conformer 2
(PDB)
1ewk (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 276 0.44   38 - 208   344 - 477
2 168 0.48   209 - 343   478 - 510

Sequence


           ________________________________________________________________________________________________________________________ 
 1ewk(B) : QRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRkPIAGVIGPGSSSVAIQVQNLLQLFDIPQI 
         :                                                                                                                          
 1ewk(A) : *RSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRkPIAGVIGPGSSSVAIQVQNLLQLFDIPQI 
           ________________________________________________________________________________________________________________________ 

           ___________________205__________________________________________________________________________________________________ 
 1ewk(B) : AYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAM 
         :                                                                                                                          
 1ewk(A) : AYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAM 
           ___________________205__________________________________________________________________________________________________ 

           _____________________________________343________________________________________________________________________________ 
 1ewk(B) : RRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAMAHG 
         :                                                                                                                          
 1ewk(A) : RRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAMAHG 
           _____________________________________343________________________________________________________________________________ 

           _______________________________________________473_______________________________________                                
 1ewk(B) : LQNMHHALCPGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKI                                
         :                                                                                                                          
 1ewk(A) : LQNMHHALCPGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKI                                
           _______________________________________________473_______________________________________                                

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
31.5
Translation
(A)
0.3
Closure
(%)
99.4
Bending Residues
( green )
  205 - 211
  343 - 347
  473 - 479
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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