DynDom - Protein Domain Motions

Atrial Natriuretic Peptide Clearance Receptor

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Atrial Natriuretic Peptide Clearance Receptor
Conformer 1 (PDB)	1jdn (A)
Conformer 2 (PDB)	1jdp (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	217	1.13	7 - 140 279 - 368
2	169	2.04	141 - 278 369 - 399

Sequence

`________________________________________________________________________________________________________________________` `1jdn(A) : **PQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEG--lPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSE` `:` `1jdp(A) : EALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGrLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSE` `________________________________________________________________________________________________________________________` `____________140_________________________________________________________________________________________________________` `1jdn(A) : YSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIE` `:` `1jdp(A) : YSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIE` `____________140_________________________________________________________________________________________________________` `______________________________278_______________________________________________________________________________________` `1jdn(A) : LFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANG` `:` `1jdp(A) : LFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANG` `______________________________278_______________________________________________________________________________________` `368__________________________________________________` `1jdn(A) : DRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENR` `:` `1jdp(A) : DRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRP***************` `368__________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	15.9
Translation (A)	-0.4
Closure (%)	91.0
Bending Residues ( green )	140 - 141 278 - 283 368 - 369
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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