2-Isopropylmalate Synthase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name 2-Isopropylmalate Synthase
  Conformer 1
(PDB)
1sr9 (B)
  Conformer 2
(PDB)
1sr9 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 401 0.81   20 - 435
2 155 0.98   436 - 641

Sequence


           ________________________________________________________________________________________________________________________ 
 1sr9(B) : TIVKPAGPPRVGQPSWNPQRASSpVNRYRPFAEEVEPIRLRNRTWPDRVIDRAPLWCAVDLRDGNQALIDPsPARKRRfDLLVRgYKEIEVGFPSASQTDFDFVREIIEQGAIPDDVTIQ 
         :                                                                                                                          
 1sr9(A) : TIVKPAGPPRVGQPSWNPQRASSpVNRYRPFAEEVEPIRLRNRTWPDRVIDRAPLWCAVDLRDGNQALIDPsPARKRRfDLLVRgYKEIEVGFPSASQTDFDFVREIIEQGAIPDDVTIQ 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1sr9(B) : VLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPERPIIFNLPATVEtTPNV 
         :                                                                                                                          
 1sr9(A) : VLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPERPIIFNLPATVEtTPNV 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1sr9(B) : YADSIEWsRNLANRESVILSLHPHNDRGTAVAAAELGFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAI 
         :                                                                                                                          
 1sr9(A) : YADSIEWsRNLANRESVILSLHPHNDRGTAVAAAELGFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAI 
           ________________________________________________________________________________________________________________________ 

           _____________________________________425________________________________________________________________________________ 
 1sr9(B) : NKGLDAkLDADAADCDVDDlWQVPYLPIDPRDVGRTYEAVIRVNkGGVAYIkTDHGLSLPRRLQIEFSQVIQK--vSPKEwDAFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKI 
         :                                                                                                                          
 1sr9(A) : NKGLDAkLDADAADCDVDDlWQVPYLPIDPRDVGRTYEAVI---kGGVAYIkTDHGLSLPRRLQIEFSQVIQKIeVSPKEwDAFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKI 
           _____________________________________425________________________________________________________________________________ 

           ________________________________________________________________________________________                                 
 1sr9(B) : NGVETEISGSGNGPLAAFVHALADVGFDVAVLDYYEHAsAGDDAQAAAYVEASVTIAStSKTVWGVGIAPSITTASLRAVVSAVNRAA                                 
         :                                                                                                                          
 1sr9(A) : NGVETEISGSGNGPLAAFVHALADVGFDVAVLDYYEHAsAGDDAQAAAYVEASVTI---sKTVWGVGIAPSITTASLRAVVSAVNRAA                                 
           ________________________________________________________________________________________                                 

Morph

Morph animation in progress.
Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
109.3
Translation
(A)
-3.5
Closure
(%)
78.3
Bending Residues
( green )
  425 - 438
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

Download and extract PyMOL PML script file Download