Glial Cell-Derived Neurotrophic Factor

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glial Cell-Derived Neurotrophic Factor
  Conformer 1
(PDB)
1agq (A)
  Conformer 2
(PDB)
1agq (C)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 45 1.39   43 - 47   67 - 107   129 - 133
2 40 0.67   48 - 66   108 - 128

Sequence


           _______47_________________66__________________________________107__________________128_______                            
 1agq(A) : NRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCEAAETMYDKILKNLSRSR--vGQACCRPVAFDDDLSFLDDSLVYHILRKHSAKRCGCI                            
         :                                                                                                                          
 1agq(C) : **GCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCEAAETMYDKILKNLSRSRRLvGQACCRPVAFDDDLSFLDDSLVYHILRKHSAKRCGCI                            
           _______47_________________66__________________________________107__________________128_______                            

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
14.4
Translation
(A)
0.5
Closure
(%)
72.2
Bending Residues
( green )
  47 - 48
  66 - 67
  107 - 108
  128 - 129
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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