DynDom - Protein Domain Motions

Atp-Binding Cassette, Sub-Family B, Member 1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Atp-Binding Cassette, Sub-Family B, Member 1
Conformer 1 (PDB)	6a6n (A)
Conformer 2 (PDB)	6a6m (A)
Window Length	11
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	431	2.55	107 - 246 393 - 683
2	146	2.75	247 - 392

Sequence

`________________________________________________________________________________________________________________________` `6a6n(A) : TGVTARRIFALAWSSSATMIVIGFIASILEGATLPAFAIVFGRMFAVFTKSKSQIEGETWKYSVGFVGIGVFEFIVAGSRTALFGIASERLARDLRVAAFSNLVEQDVTYFDRRKAGEL` `:` `6a6m(A) : TTGVTARRIFALAWSSSATMIVIGFIASILEGATLPAFAIVFGRMFAVFTKSKSQIEGETWKYSVGFVGIGVFEFIVAGSRTALFGIASERLARDLRVAAFSNLVEQDVTYFDRRKAGEL` `________________________________________________________________________________________________________________________` `_______________________246______________________________________________________________________________________________` `6a6n(A) : GGKLNNDVQVIQYSFSKLGAVLFNLAQCVVGIIVAFIFAPALTGVLIALSPLVVLAGAAQMIEMSGNTKRSSEAYASAGSVAAEVFSNIRTTKAFEAERYETQRYGSKLDPLYRLGRRRY` `:` `6a6m(A) : GGKLNNDVQVIQYSFSKLGAVLFNLAQCVVGIIVAFIFAPALTGVLIALSPLVVLAGAAQMIEMSGNTKRSSEAYASAGSVAAEVFSNIRTTKAFEAERYETQRYGSKLDPLYRLGRRRY` `_______________________246______________________________________________________________________________________________` `_________________________________________________392____________________________________________________________________` `6a6n(A) : ISDGLFFGLSMLVIFCVYALALWWGGQLIARGSLNLGNLLAAFFSAILGFMGVGQAAQVWPDVTRGLGAGGELFAMIDRVPQYRRPDPGAEVVTQPLVLKQGIVFENVHFRYPTRMNVEV` `:` `6a6m(A) : ISDGLFFGLSMLVIFCVYALALWWGGQLIARGSLNLGNLLAAFFSAILGFMGVGQAAQVWPDVTRGLGAGGELFAMIDRVPQYRRPDPGAEVVTQPLVLKQGIVFENVHFRYPTRMNVEV` `_________________________________________________392____________________________________________________________________` `________________________________________________________________________________________________________________________` `6a6n(A) : LRGISLTIPNGKTVAIVGGSGAGKSTIIQLLMRFYDIEPQGGGLLLFDGTPAWNYDFHALRSQIGLVSQEPVLFSGTIRDNILYGKRDATDEEVIQALREANAYSFVMALPDGLDTEVGE` `:` `6a6m(A) : LRGISLTIPNGKTVAIVGGSGAGKSTIIQLLMRFYDIEPQGGGLLLFDGTPAWNYDFHALRSQIGLVSQEPVLFSGTIRDNILYGKRDATDEEVIQALREANAYSFVMALPDGLDTEVGE` `________________________________________________________________________________________________________________________` `_____________________________________________________________________________________________________________` `6a6n(A) : RGLALSGGQKQRIAIARAILKHPTLLCLDESTSALDAESEALVQEALDRMMASDGVTSVVIAHRLSTVARADLILVMQDGVVVEQGNHSELMALGPSGFYYQLVEKQL` `:` `6a6m(A) : RGLALSGGQKQRIAIARAILKHPTLLCLDESTSALDAESEALVQEALDRMMASDGVTSVVIAHRLSTVARADLILVMQDGVVVEQGNHSELMALGPSGFYYQLVEKQLA` `_____________________________________________________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	28.0
Translation (A)	4.4
Closure (%)	99.8
Bending Residues ( green )	246 - 247 392 - 393
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

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