3C-Like Protease

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name 3C-Like Protease
  Conformer 1
(PDB)
4in1 (A)
  Conformer 2
(PDB)
4inh (B)
  Window Length 15
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 130 1.04   7 - 99   123 - 167
2 23 1.01   100 - 122

Sequence


           _____________________________________________________________________________________________________99_________________ 
 4in1(A) : ***SAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQGRLVHG 
         :                                                                                                                          
 4inh(B) : DDDKAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQGRLVHG 
           _____________________________________________________________________________________________________99_________________ 

           ___122___________________________________________________                                                                
 4in1(A) : QSGMLLTlGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGNTVVCAVQAGEGEINFE                                                                
         :                                                                                                                          
 4inh(B) : QSGMLLTGgTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGNTVVCAVQAG*******                                                                
           ___122___________________________________________________                                                                

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
10.1
Translation
(A)
0.1
Closure
(%)
74.5
Bending Residues
( green )
  99 - 100
  122 - 139
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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