DynDom - Protein Domain Motions

Fusion Protein Of T-Complex Protein 1 Subunit Gamma,rep- His-Cbp And T-Complex Protein 1 Subunit Gamma

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Fusion Protein Of T-Complex Protein 1 Subunit Gamma,rep- His-Cbp And T-Complex Protein 1 Subunit Gamma
Conformer 1 (PDB)	6ks6 (G)
Conformer 2 (PDB)	5gw5 (G)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	104	1.44	144 - 223 436 - 469
2	248	1.77	15 - 143 470 - 588
3	152	2.02	224 - 435

Sequence

`________________________________________________________________________________________________________________________` `6ks6(G) : VFMNASQERTTGRQAQISNITAAKAVADVIRTCLGPKAMLKMLLDPMGGLVLTNDGHAILREIDVAHPAAKSMLELSRTQDEEVGDGTTTVIILAGEILAQCAPYLIEKNIHPVIIIQAL` `:` `5gw5(G) : *****ERTTGRQAQISNITAAKAVADVIRTCLGPKAMLKMLLDPMGGLVLTNDGHAILREIDVAHPAAKSMLELSRTQDEEVGDGTTTVIILAGEILAQCAPYLIEKNIHPVIIIQAL` `________________________________________________________________________________________________________________________` `_______________143_____________________________________________________________________________223______________________` `6ks6(G) : KKALTDALEVIKQVSKPVDVENDAAMKKLIQASIGTKYVIHWSEKMCELALDAVKTVRKD----------fEIDIKRYVRVEKIPGGDVLDSRVLKGVLLNKDVVHPKMSRHIENPRVVL` `:` `5gw5(G) : KKALTDALEVIKQVSKPVDVENDAAMKKLIQASIGTKYVIHWSEKMCELALDAVKTVRKDLGQTVEGEPNFEIDIKRYVRVEKIPGGDVLDSRVLKGVLLNKDVVHPKMSRHIENPRVVL` `_______________143_____________________________________________________________________________223______________________` `________________________________________________________________________________________________________________________` `6ks6(G) : LDCPLEYKKGESQTNIEIEKEEDWNRILQIEEEQVQLMCEQILAVRPTLVITEKGVSDLAQHYLLKGGCSVLRRVKKSDNNRIARVTGATIVNRVEDLKESDVGTNCGLFKVEMIGDEYF` `:` `5gw5(G) : LDCPLEYKKGESQTNIEIEKEEDWNRILQIEEEQVQLMCEQILAVRPTLVITEKGVSDLAQHYLLKGGCSVLRRVKKSDNNRIARVTGATIVNRVEDLKESDVGTNCGLFKVEMIGDEYF` `________________________________________________________________________________________________________________________` `_______435__________________________________469_________________________________________________________________________` `6ks6(G) : SFLDNCKEsGLQKACTIMLRGGSKDILNEIDRNLQDAMAVARNVMLSPSLSPGGGATEMAVSVKLAEKAKQLEGIQQWPYQAVADAMECIPRTLIQNAGGDPIRLLSQLRAKHAQGNFTT` `:` `5gw5(G) : SFLDNCKEP---KACTIMLRGGSKDILNEIDRNLQDAMAVARNVMLSPSLSPGGGATEMAVSVKLAEKAKQLEGIQQWPYQAVADAMECIPRTLIQNAGGDPIRLLSQLRAKHAQGNFTT` `_______375__________________________________409_________________________________________________________________________` `__________________________________________________` `6ks6(G) : GIDGDKGKIVDMVSYGIWEPEVIKQQSVKTAIESACLLLRVDDIVSGVRK` `:` `5gw5(G) : GIDGDKGKIVDMVSYGIWEPEVIKQQSVKTAIESACLLLRVDDIVSGV` `__________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	29.6
Translation (A)	0.4
Closure (%)	99.5
Bending Residues ( green )	143 - 144 469 - 470
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	20.3
Translation (A)	0.2
Closure (%)	59.9
Bending Residues ( green )	223 - 224 435 - 436
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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