Histone-Lysine N-Methyltransferase, H3 Lysine-79 Specific

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Histone-Lysine N-Methyltransferase, H3 Lysine-79 Specific
  Conformer 1
(PDB)
1u2z (C)
  Conformer 2
(PDB)
1u2z (B)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 206 0.5   338 - 348   353 - 435   447 - 558
2 158 0.54   179 - 337   349 - 352   436 - 446   579 - 579

Sequence


           ________________________________________________________________________________________________________________________ 
 1u2z(C) : SSTFVDWNGPCLRLQYPLFDIEYLRSHEIYSGTPIQSISLRTtTAKLQSILFSNYMEEYKVDFKRSTAIYNPMSEIGKLIEYSCLVFLPSPYAEQLKETILPDLNASFDNSDTKGFVNAI 
         :                                                                                                                          
 1u2z(B) : *STFVDWNGPCLRLQYPLFDIEYLRSHEIYSGTPIQSISLRTtTAKLQSILFSNYMEEYKVDFKRSTAIYNPMSEIGKLIEYSCLVFLPSPYAEQLKETILPDLNASFDNSDTKGFVNAI 
           ________________________________________________________________________________________________________________________ 

           ______________________337________348_352________________________________________________________________________________ 
 1u2z(C) : NLYNKMIREIPRQRIIDHLETIDKIPRSFIHDFLHIVYTRSIHPQANKLKHYKAFSNYVYGELLPNFLSDVYQQCQLKKGDTFMDLGSGVGNCVVQAALECGCALSFGCEIMDDASDLTI 
         :                                                                                                                          
 1u2z(B) : NLYNKMIREIPRQRIIDHLETIDKIPRSFIHDFLHIVYTRSIHPQANKLKHYKAFSNYVYGELLPNFLSDVYQQCQLKKGDTFMDLGSGVGNCVVQAALECGCALSFGCEIMDDASDLTI 
           ______________________337________348_352________________________________________________________________________________ 

           435________446__________________________________________________________________________________________________________ 
 1u2z(C) : LQYEELKKRCKLYGMRLNNVEFSLKKSFVDNNRVAELIPQCDVILVNNFLFDEDLNKKVEKILQTAKVGCKIISLKSLRSLTYQINFYNVENIFNRLKVQRYDLKEDSVSWTHSGGEYYI 
         :                                                                                                                          
 1u2z(B) : LQYEELKKRCKLYGMRLNNVEFSLKKSFVDNNRVAELIPQCDVILVNNFLFDEDLNKKVEKILQTAKVGCKIISLKSLRSLTYQINFYNVENIFNRLKVQRYDLKEDSVSWTHSGGEYYI 
           435________446__________________________________________________________________________________________________________ 

           ___558___________________                                                                                                
 1u2z(C) : STVMEDVDESLFSPAARrtPVKYTR                                                                                                
         :                                                                                                                          
 1u2z(B) : STVMEDVDESLFSP----rpVKYT*                                                                                                
           ___558___________________                                                                                                

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
4.9
Translation
(A)
-0.1
Closure
(%)
56.0
Bending Residues
( green )
  337 - 338
  348 - 349
  352 - 353
  435 - 436
  446 - 447
  558 - 579
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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