DynDom - Protein Domain Motions

Atp-Dependent Molecular Chaperone Hsp82

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Atp-Dependent Molecular Chaperone Hsp82
Conformer 1 (PDB)	2cg9 (A)
Conformer 2 (PDB)	2cge (A)
Window Length	7
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	220	2.35	276 - 481 497 - 519
2	152	2.01	482 - 496 520 - 669

Sequence

`________________________________________________________________________________________________________________________` `2cg9(A) : ASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFG` `:` `2cge(A) : **********************************************************************************************************************` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2cg9(A) : VGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEeEVQEIEELNKTKPLWTRNPSDITQ` `:` `2cge(A) : ********************************************************************************************************TKPLWTRNPSDITQ` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2cg9(A) : EEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPF---------nNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNE` `:` `2cge(A) : EEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNE` `________________________________________________________________________________________________________________________` `________________________________________________________________________481____________496_________________516__________` `2cg9(A) : IAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITK` `:` `2cge(A) : IAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITK` `________________________________________________________________________481____________496_________________516__________` `________________________________________________________________________________________________________________________` `2cg9(A) : DFELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQA-------------kTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLL` `:` `2cge(A) : DFELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLL` `________________________________________________________________________________________________________________________` `_______________________________` `2cg9(A) : YETALLTSGFSLDEPTSFASRINRLISLGLN` `:` `2cge(A) : YETALLTSGFSLDEPTSFASRINRLISLGLN` `_______________________________`

Morph

Morph animation in progress.
Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.

play backwards

pause

play forwards

Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	16.1
Translation (A)	-0.2
Closure (%)	91.4
Bending Residues ( green )	113 - 114
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

D-LACTATE DEHYDROGENASE

PyMOL Script

Download and extract PyMOL PML script file

Download