Casein Kinase 1 Gamma 2 Isoform

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Casein Kinase 1 Gamma 2 Isoform
  Conformer 1
(PDB) 		2c47 (B)
  Conformer 2
(PDB) 		2chl (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 240 0.78   7 - 7   11 - 11   20 - 23   31 - 31   55 - 70   78 - 295
2 43 1.29   6 - 6   8 - 10   12 - 19   24 - 30   32 - 54   72 - 77

Sequence


           _______6__10___________23_____30______________________54______________70_____77_________________________________________ 
 2c47(B) : *****PNFRVGKKIg-----ELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGP-gKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHT 
         :                                                                                                                          
 2chl(A) : VLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHS 
           ______32__36___________49_____56______________________80______________96____103_________________________________________ 

           ________________________________________________________________________________________________________________________ 
 2c47(B) : KSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEV 
         :                                                                                                                          
 2chl(A) : KNLIYRDVKPENFLIGRPGNKTQQVIHIIDFALAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEV 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________________________                                                             
 2c47(B) : LCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPI                                                             
         :                                                                                                                          
 2chl(A) : LCENFPE-MATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTP*                                                             
           ____________________________________________________________                                                             

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		9.7
Translation
(A) 		0.3
Closure
(%) 		49.5
Bending Residues
( green ) 		  6 - 8
  10 - 20
  23 - 24
  30 - 32
  54 - 55
  70 - 72
  77 - 78
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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