Humanized Antibody D3h44

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Humanized Antibody D3h44
  Conformer 1
(PDB)
1pg7 (H)
  Conformer 2
(PDB)
1jps (H)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 115 1.04   3 - 113
2 94 0.63   114 - 211

Sequence


           _________________________________________________________________________________________________________________112____ 
 1pg7(H) : EVQLVESGGGLVQPGGSLRLSCAASGFNIKEYYMHWVRQAPGKGLEWVGLIDPEQGNTIYDPKFQDRATISADNSKNTAYLQMNSLRAEDTAVYYCARDTAAYFDYWGQGTLVTVSSAST 
         :                                                                                                                          
 1jps(H) : EVQLVESGGGLVQPGGSLRLSCAASGFNIKEYYMHWVRQAPGKGLEWVGLIDPEQGNTIYDPKFQDRATISADNSKNTAYLQMNSLRAEDTAVYYCARDTAAYFDYWGQGTLVTVSSAST 
           _________________________________________________________________________________________________________________116____ 

           _____________________________________________________________________________________________                            
 1pg7(H) : KGPSVFPLAPSSgGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP                            
         :                                                                                                                          
 1jps(H) : KGPSVFPLAPSSgGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP                            
           _____________________________________________________________________________________________                            

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
51.2
Translation
(A)
0.4
Closure
(%)
95.9
Bending Residues
( green )
  112 - 118
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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