Monoclonal Antibody 2D12.5, Lambda Light Chain

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Monoclonal Antibody 2D12.5, Lambda Light Chain
  Conformer 1
(PDB) 		1gig (L)
  Conformer 2
(PDB) 		1q0x (L)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 107 0.6   3 - 109
2 99 0.99   110 - 208

Sequence


           _________________________________________________________________________________________________________108____________ 
 1gig(L) : QAVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQEKPDHLFTGLIGGTNNRAPGVPARFSGSLIGDKAALTITGAQTEDEAIYFCALWYSNHWVFGGGTKLTVLGQPKSSPSVTL 
         :                                                                                                                          
 1q0x(L) : DAVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQEKPDHLFTGLIGGTNNRAPGVPARFSGSLIGDKAALTITGAQTEDEAIYFCALWSNNKLVFGGGTKLTVLGQPKSSPTVTL 
           _________________________________________________________________________________________________________106____________ 

           ____________________________________________________________________________________________                             
 1gig(L) : FPPSSEELETNKATLVCTITDFYPGVVTVDWKVDGTPVTQGMETTQPSKQSNNKYMASSYLTLTARAWERHSSYSCQVTHEGHTVEKSLS**                             
         :                                                                                                                          
 1q0x(L) : FPPSSEELSTAKATLVCTITDFYPGVVTVDWKVDGTPVTAGMETTQPSKQSNNKYMASSYLTLTARAWERHSSYSCQVTHEGHSSNKTLSRA                             
           ____________________________________________________________________________________________                             

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		41.0
Translation
(A) 		1.6
Closure
(%) 		67.2
Bending Residues
( green ) 		  108 - 114
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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