Mannitol Dehydrogenase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Mannitol Dehydrogenase
  Conformer 1
(PDB)
1lj8 (A)
  Conformer 2
(PDB)
1m2w (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 254 0.4   4 - 88   92 - 129   135 - 136   147 - 188   190 - 232   237 - 283   296 - 296
2 223 0.48   89 - 91   130 - 134   137 - 145   189 - 189   233 - 236   284 - 295   297 - 490

Sequence


           ____________________________________________________________________________________88__________________________________ 
 1lj8(A) : KLNKQNLTQLAPEVKLPAYTLADTRQGIAHIGVGGFHRAHQAYYTDALnTGEGLDWSICGVGLRSEDRKARDDLAGQDYLFTLYELGDTDDTEVRVIGSISDlLAEDSAQALIDKLASPE 
         :                                                                                                                          
 1m2w(A) : KLNKQNLTQLAPEVKLPAYTLADTRQGIAHIGVGGFHRAHQAYYTDALnTGEGLDWSICGVGLRSEDRKARDDLAGQDYLFTLYELGDTDDTEVRVIGSISDlLAEDSAQALIDKLASPE 
           ____________________________________________________________________________________88__________________________________ 

           ___129__134________145______________________________________188________________________________________232______________ 
 1lj8(A) : IRIVSLTITEGGYCIDDSNGEFaHLPQIQHDLAHPSSPKTVFGFICAALTQRRAAGIPAFTVsCDNLPHNGAVTRKALLAFAALHNAELHDWIKAHVSFPNAvDRITPtSTAHRLQLHDE 
         :                                                                                                                          
 1m2w(A) : IRIVSLTITEGGYCIDDSNGEFaHLPQIQHDLAHPSSPKTVFGFICAALTQRRAAGIPAFTVsCDNLPHNGAVTRKALLAFAALHNAELHDWIKAHVSFPNAvDRITPtSTAHRLQLHDE 
           ___129__134________145______________________________________188________________________________________232______________ 

           _________________________________283_287________________________________________________________________________________ 
 1lj8(A) : HGIDDAWPVVCEPFVQWVLEDKFVNGRPAWEKVGVQFTDDVTPYEEkIGLLNGSHLALTYLGFLKGYRFVHETnDPLFVAYrAYdLDVTPNLAPVPGIDLTDYKQTLVDRFSNQAIADQL 
         :                                                                                                                          
 1m2w(A) : HGIDDAWPVVCEPFVQWVLEDKFVNGRPAWEKVGVQFTDDVTPYEEkIGLLNGSHLALTYLGFLKGYRFVHETnDPLFVAYrAYdLDVTPNLAPVPGIDLTDYKQTLVDRFSNQAIADQL 
           _________________________________283_287________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1lj8(A) : ERVCSDGSSKFPKFTVPTINRLIADGRETERAALVVAAWALYLKGVDENGVSYTIPDPRAEFCQGLVSDDALISQRLLAVEEIFGTAIPNSPEFVAAFERCYGSLRDNGVTTTLKHLLKK 
         :                                                                                                                          
 1m2w(A) : ERVCSDGSSKFPKFTVPTINRLIADGRETERAALVVAAWALYLKGVDENGVSYTIPDPRAEFCQGLVSDDALISQRLLAVEEIFGTAIPNSPEFVAAFERCYGSLRDNGVTTTLKHLLKK 
           ________________________________________________________________________________________________________________________ 

           _                                                                                                                        
 1lj8(A) : P                                                                                                                        
         :                                                                                                                          
 1m2w(A) : P                                                                                                                        
           _                                                                                                                        

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
5.2
Translation
(A)
0.2
Closure
(%)
53.5
Bending Residues
( green )
  88 - 95
  129 - 130
  134 - 137
  145 - 147
  188 - 192
  232 - 238
  283 - 284
  287 - 297
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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