Mothers Against Decapentaplegic Homolog 3

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Mothers Against Decapentaplegic Homolog 3
  Conformer 1
(PDB) 		1u7f (C)
  Conformer 2
(PDB) 		1mk2 (A)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 140 0.84   233 - 318   323 - 344   371 - 402
2 41 0.77   319 - 322   345 - 370   403 - 413

Sequence


           ________________________________________________________________________________________________318_322_________________ 
 1u7f(C) : **********AFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCN 
         :                                                                                                                          
 1mk2(A) : DLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCN 
           ________________________________________________________________________________________________317_321_________________ 

           __344_______________________370_____________________________402_____________________                                     
 1u7f(C) : LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSv                                     
         :                                                                                                                          
 1mk2(A) : LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGS*******                                     
           __343_______________________369_____________________________401_____________________                                     

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		9.7
Translation
(A) 		0.8
Closure
(%) 		99.6
Bending Residues
( green ) 		  318 - 319
  322 - 323
  344 - 345
  370 - 371
  402 - 403
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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