Myosin II Heavy Chain

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Myosin II Heavy Chain
  Conformer 1
(PDB) 		1jwy (A)
  Conformer 2
(PDB) 		1lvk  
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 593 1.09   15 - 40   50 - 60   90 - 101   110 - 494   521 - 691   765 - 768
2 138 1.67   41 - 49   61 - 89   102 - 109   495 - 520   692 - 764

Sequence


           _____________27____________________49_________60___________________________89_________101_____109_______________________ 
 1jwy(A) : DPIHDRTSDYHKYLKVKQ-----fKLTVSDKRYIWYNPDPKERDSYECGEIVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVRYNQDLIYTYSGL 
         :                                                                                                                          
 1lvk    : NPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECGEIVSETSDSFTFKTSDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVRYNQDLIYTYSGL 
           _____________16____________________38_________49___________________________78__________90______98_______________________ 

           ________________________________________________________________________________________________________________________ 
 1jwy(A) : FLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAG---sGVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIE 
         :                                                                                                                          
 1lvk    : FLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRNQAgVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIE 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1jwy(A) : IQFNSAGFISGASIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEKGAG 
         :                                                                                                                          
 1lvk    : IQFNNAGFISGASIQSYLLEKSRVVFQSTSERNYHIFYQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKGVSDEDEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEKGAG 
           ________________________________________________________________________________________________________________________ 

           ____________________________________________________________________________________________________________________494_ 
 1jwy(A) : EGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDISGFEIFKVNSFEQLCINYTNEKLQQFFNH 
         :                                                                                                                          
 1lvk    : EGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCSERKAYFIGVLDISGFEIFKVNSFEQLCINYTNEKLQQFFNH 
           ____________________________________________________________________________________________________________________483_ 

           ______________________520_______________________________________________________________________________________________ 
 1jwy(A) : HMFKLEQEEYLKEKINWTFIDFGLDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSS 
         :                                                                                                                          
 1lvk    : HMFKVEQEKYLKEKIN-------lDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSS 
           ______________________509_______________________________________________________________________________________________ 

           _________________________________________________________________________691____________________________________________ 
 1jwy(A) : DNVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDAEDSQKATD 
         :                                                                                                                          
 1lvk    : DNVVTKLFNDPNIASRA-----fLTVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYDLAPNVPRDAEDSQKATD 
           _________________________________________________________________________680____________________________________________ 

           __________________________764____________                                                                                
 1jwy(A) : AVLKHLNIDPEQYRFGITKIFFRAGQLARIEEAREQRISEI                                                                                
         :                                                                                                                          
 1lvk    : AVLKHLNIDPEQFRFGITKIFFRAGQLARIEEARE******                                                                                
           __________________________753____________                                                                                

Morph
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Status: Initialising

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		12.6
Translation
(A) 		0.6
Closure
(%) 		65.1
Bending Residues
( green ) 		  27 - 44
  49 - 50
  60 - 61
  89 - 90
  101 - 102
  109 - 110
  494 - 495
  520 - 521
  691 - 692
  764 - 768
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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