DynDom - Protein Domain Motions

Phosphoenolpyruvate-Protein Phosphotransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Phosphoenolpyruvate-Protein Phosphotransferase
Conformer 1 (PDB)	2hwg (A)
Conformer 2 (PDB)	2hwg (B)
Window Length	15
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	24	1.26	18 - 28 140 - 152
2	402	0.36	9 - 14 155 - 566
3	109	0.6	29 - 139

Sequence

`___________14____________28_____________________________________________________________________________________________` `2hwg(A) : ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIlLEDEELEQEIIALIKDKHtADAAAHEVIEGQASALEELDDEYL` `:` `2hwg(B) : ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIlLEDEELEQEIIALIKDKHtADAAAHEVIEGQASALEELDDEYL` `___________14____________28_____________________________________________________________________________________________` `_____________139__________152___________________________________________________________________________________________` `2hwg(A) : KERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTStSIaRSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKrAVQEQV` `:` `2hwg(B) : KERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTStSIaRSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKrAVQEQV` `_____________139__________152___________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2hwg(A) : ASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFdRDALPTEEEQFAAYKAVAEACGSQAVIVRTdIGGDKELPYnFPKEENPFLGWRAIRIAdRREIL` `:` `2hwg(B) : ASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFdRDALPTEEEQFAAYKAVAEACGSQAVIVRTdIGGDKELPYnFPKEENPFLGWRAIRIAdRREIL` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2hwg(A) : RDQLRAILRASAFGKLRIfPiISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVvETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDiSHLYQPsPSVLNLIKQVIDASHAE` `:` `2hwg(B) : RDQLRAILRASAFGKLRIfPiISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVvETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDiSHLYQPsPSVLNLIKQVIDASHAE` `________________________________________________________________________________________________________________________` `__________________________________________________________________________` `2hwg(A) : GKWTGcGELAGDERATLLLLGgLDEFSsAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELtLVNKFIEEKT` `:` `2hwg(B) : GKWTGcGELAGDERATLLLLGgLDEFSsAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELtLVNKFIEEKT` `__________________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.

play backwards

pause

play forwards

Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	15.8
Translation (A)	0.5
Closure (%)	97.1
Bending Residues ( green )	14 - 18 152 - 156
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	11.5
Translation (A)	-0.1
Closure (%)	81.1
Bending Residues ( green )	28 - 31 139 - 140
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Mixed

PyMOL Script

Download and extract PyMOL PML script file

Download