Thymidine Phosphorylase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Thymidine Phosphorylase
  Conformer 1
(PDB) 		2tpt  
  Conformer 2
(PDB) 		1otp  
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 321 0.71   69 - 82   87 - 162   193 - 196   199 - 212   219 - 221   226 - 236   238 - 436
2 115 0.56   3 - 68   83 - 86   163 - 192   197 - 198   213 - 218   222 - 225   237 - 237   437 - 438

Sequence


           _________________________________________________________________67_____________82__86__________________________________ 
 2tpt    : LFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHT 
         :                                                                                                                          
 1otp    : LFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHT 
           _________________________________________________________________67_____________82__86__________________________________ 

           _______________________________________162_________________________190___196_____________212___218___224_________236____ 
 2tpt    : GGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLT 
         :                                                                                                                          
 1otp    : GGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLT 
           _______________________________________162_________________________190___196_____________212___218___224_________236____ 

           ________________________________________________________________________________________________________________________ 
 2tpt    : DMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALG 
         :                                                                                                                          
 1otp    : DMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALG 
           ________________________________________________________________________________________________________________________ 

           _________________________________________________________________________436____                                         
 2tpt    : MAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENNWQEAAKAVKAAIKLADKAPESTPTVYRRISE                                         
         :                                                                                                                          
 1otp    : MAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENNWQEAAKAVKAAIKLADKAPESTPTVYRRISE                                         
           _________________________________________________________________________436____                                         

Morph
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Status: Initialising

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		8.2
Translation
(A) 		0.6
Closure
(%) 		60.2
Bending Residues
( green ) 		  67 - 69
  82 - 83
  86 - 87
  162 - 163
  190 - 193
  196 - 199
  212 - 213
  218 - 219
  221 - 222
  224 - 226
  236 - 238
  436 - 437
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

PyMOL Script

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