Conformer 1 |
2hre(D)
|
Conformer 2 |
2hrc(B)
|
Radius gyration for conformer 1 |
20.53 A
|
Radius gyration for conformer 2 |
20.63 A
|
EC Number |
4.99.1.1
|
Click here to see
the DynDom results
or
the famliy
|
Trigger ligands
|
PP9604
PP9606
|
Trigger ligands in which conformation
|
Conformation 1
|
Conformaton with trigger ligands is compact
|
Yes
|
Spanning ligands
|
Yes
|
Residues in enzyme contacting ligands
|
ALA336
ARG115
GLY306
GLY77
GLY78
HIS263
HIS341
ILE111
ILE119
ILE132
ILE342
LEU265
LEU89
LEU92
LEU98
LYS343
MET308
MET76
MET99
PHE110
PHE337
PHE88
PHE93
PRO102
PRO266
PRO307
SER130
SER197
THR198
TRP310
TYR123
TYR191
TYR276
VAL305
|
Residues in extended bending regions contacting ligands
|
GLY77
GLY78
ILE119
ILE132
MET76
SER130
TYR123
|
Residues in extended bending regions making H-bonds or salt-bridges with ligands
|
SER130
TYR123
|
Residues in extended bending regions with an H-bond between its main
chain and ligands
|
Null
|
Click here to see the details of H-bonds between ligands and enzyme in PDF format generated by LIGPLOT
|