DynDom - Protein Domain Motions

Phosphomannomutase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Phosphomannomutase
Conformer 1 (PDB)	1k2y (X)
Conformer 2 (PDB)	1p5d (X)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	111	0.68	247 - 249 259 - 266 280 - 306 310 - 320 323 - 327 365 - 377 396 - 419 432 - 450 452 - 452
2	299	0.64	11 - 246 250 - 258 267 - 279 307 - 309 321 - 322 328 - 364
3	39	0.61	378 - 395 420 - 431 451 - 451 453 - 460

Sequence

`________________________________________________________________________________________________________________________` `1k2y(X) : KAPTLPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGAHNPPDYNGFKIVVAGE` `:` `1p5d(X) : ****LPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTG-hNPPDYNGFKIVVAGE` `________________________________________________________________________________________________________________________` `_______________________________________________________________________________________________________________________2` `1k2y(X) : TLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGD` `:` `1p5d(X) : TLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGD` `_______________________________________________________________________________________________________________________2` `46_________258_____266_______276___________________________306___________320_________________________________________364` `1k2y(X) : GDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVF` `:` `1p5d(X) : GDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVF` `46_________258_____266_______276___________________________306___________320_________________________________________364` `__________377_______________395_____________________419_________431________________450_____________` `1k2y(X) : SAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF` `:` `1p5d(X) : SAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF` `__________377_______________395_____________________419_________431________________450_____________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	9.6
Translation (A)	-0.2
Closure (%)	98.9
Bending Residues ( green )	246 - 247 249 - 250 258 - 259 266 - 267 276 - 280 306 - 310 320 - 330 364 - 366
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	6.7
Translation (A)	-0.3
Closure (%)	95.7
Bending Residues ( green )	377 - 378 395 - 396 419 - 420 431 - 432 450 - 453
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Shear

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