Alpha-1-Antitrypsin

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Alpha-1-Antitrypsin
  Conformer 1
(PDB)
5io1 (A)
  Conformer 2
(PDB)
3t1p (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 329 9.77   26 - 360
2 32 0.7   361 - 392

Sequence


           ________________________________________________________________________________________________________________________ 
 5io1(A) : NKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAF 
         :                                                                                                                          
 3t1p(A) : NKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAF 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 5io1(A) : TVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHL 
         :                                                                                                                          
 3t1p(A) : TVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHSKKLSSWVLLMKYLGNATAIFFLPDEGKLQHL 
           ________________________________________________________________________________________________________________________ 

           _____________________________________________________________________________343________________________________________ 
 5io1(A) : ENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDKKGCE------lEAIPRSIPPEVKFNKPFVFLMIEQNTKSPL 
         :                                                                                                                          
 3t1p(A) : ENELTHDIITKFLENEDRRSASLHLPKLCITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLCIDEKGTEAAGAMFLEAIPRSIPPEVKFNKPFVFLMIEQNTKSPL 
           _____________________________________________________________________________343________________________________________ 

           ___________                                                                                                              
 5io1(A) : FMGKVVNPTQK                                                                                                              
         :                                                                                                                          
 3t1p(A) : FMGKVVNPTQK                                                                                                              
           ___________                                                                                                              

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
121.2
Translation
(A)
1.4
Closure
(%)
98.0
Bending Residues
( green )
  343 - 361
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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