Coproporphyrinogen III Oxidase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Coproporphyrinogen III Oxidase
  Conformer 1
(PDB)
1tlb (Q)
  Conformer 2
(PDB)
1tkl (B)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 276 1.11   13 - 77   92 - 93   110 - 139   147 - 325
2 24 2.67   78 - 91   107 - 109   140 - 146

Sequence


           ______________________________________________________________________74_______________91_______________________________ 
 1tlb(Q) : APQDPRNLPIRQQMEALIRRKQAEITQGLESIDTVKFHADTWTRGNDGGGGTSMVIQDGTTFEKGGVNVSVVYGQLSPAAVSAMKADHKNLRLPEDPKTGLPVTDGVKFFACGLSMVIHP 
         :                                                                                                                          
 1tkl(B) : *PQDPRNLPIRQQMEALIRRKQAEITQGLESIDTVKFHADTWTRGNDGGGGTSMVIQDGTTFEKGGVNVSVVYGQLSPAAVSAMKADHKNLRLPEDPKTGLPVTDGVKFFACGLSMVIHP 
           ______________________________________________________________________74_______________91_______________________________ 

           _____________138_____146________________________________________________________________________________________________ 
 1tlb(Q) : VNPHAPTTHLNYRYFETWNQDGTPQTWWFGGGADLTPSYLYEEDGQLFHQLHKDALDKHDTALYPRFKKWCDEYFYITHRKETRGIGGIFFDDYDERDPQEILKMVEDCFDAFLPSYLTI 
         :                                                                                                                          
 1tkl(B) : VNPHAPTTHLNYRYFETWNQDGTPQTWWFGGGADLTPSYLYEEDGQLFHQLHKDALDKHDTALYPRFKKWCDEYFYITHRKETRGIGGIFFDDYDERDPQEILKMVEDCFDAFLPSYLTI 
           _____________138_____146________________________________________________________________________________________________ 

           ______________________________________________________________________________________                                   
 1tlb(Q) : VKRRKDMPYTKEEQQWQAIRRGRYVEFNLIYDRGTQFGLRTPGSRVESILMSLPEHASWLYNHHPAPGSREAKLLEVTTKPREWVK                                   
         :                                                                                                                          
 1tkl(B) : VKRRKDMPYTKEEQQWQAIRRGRYVEFNLIYDRGTQFGLRTPGSRVESILMSLPEHASWLYNHHPAPGSREAKLLEVTTKPREWVK                                   
           ______________________________________________________________________________________                                   

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
38.0
Translation
(A)
0.6
Closure
(%)
90.7
Bending Residues
( green )
  74 - 78
  91 - 112
  138 - 140
  146 - 149
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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