Atp-Dependent RNA Helicase Ddx48

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Atp-Dependent RNA Helicase Ddx48
  Conformer 1
(PDB)
2j0u (A)
  Conformer 2
(PDB)
2j0s (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 202 1.21   40 - 241
2 160 3.37   242 - 406

Sequence


           ________________________________________________________________________________________________________________________ 
 2j0u(A) : *****************PTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSVSVLQCLDIQVRETQALILAPTRELAVQVQKGLLALGDYMNVQCHAC 
         :                                                                                                                          
 2j0s(A) : EDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHAC 
           ________________________________________________________________________________________________________________________ 

           __________________________________________________________________________________________________241___________________ 
 2j0u(A) : IGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVER 
         :                                                                                                                          
 2j0s(A) : IGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVER 
           __________________________________________________________________________________________________241___________________ 

           ________________________________________________________________________________________________________________________ 
 2j0u(A) : EEWKFDTLCDLYD---iTQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWAR--dVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAVNF 
         :                                                                                                                          
 2j0s(A) : EEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINF 
           ________________________________________________________________________________________________________________________ 

           _______________________________                                                                                          
 2j0u(A) : VKNDDIRVLRDIEQYYSTQIDEMPMNVA***                                                                                          
         :                                                                                                                          
 2j0s(A) : VKNDDIRILRDIEQYYSTQIDEMPMNVADLI                                                                                          
           _______________________________                                                                                          

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
147.8
Translation
(A)
15.0
Closure
(%)
44.8
Bending Residues
( green )
  241 - 248
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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