Carminomycin 4-O-Methyltransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Carminomycin 4-O-Methyltransferase
  Conformer 1
(PDB)
1tw2 (B)
  Conformer 2
(PDB)
1tw3 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 175 1.23   146 - 283   310 - 311   315 - 349
2 161 0.75   14 - 145   284 - 309   312 - 314

Sequence


           ________________________________________________________________________________________________________________________ 
 1tw2(B) : EPTVAARPQQIDALRTLIRLGSLHTPMVVRTAATLRLVDHILAGARTVKALAARTDTRPEALLRLIRHLVAIGLLEEDAPGEFVPTEVGELLADDHPAAQRAWHDLTQAVARADISFTRL 
         :                                                                                                                          
 1tw3(A) : *********QIDALRTLIRLGSLHTPMVVRTAATLRLVDHILAGARTVKALAARTDTRPEALLRLIRHLVAIGLLEEDAPGEFVPTEVGELLADDHPAAQRAWHDLTQAVARADISFTRL 
           ________________________________________________________________________________________________________________________ 

           ____________________145_________________________________________________________________________________________________ 
 1tw2(B) : PDAIRTGRPTYESIYGKPFYEDLAGRPDLRASFDSLLACDQDVAFDAPAAAYDWTNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDVVEGDFFEPLP 
         :                                                                                                                          
 1tw3(A) : PDAIRTGRPTYESIYGKPFYEDLAGRPDLRASFDSLLACDQDVAFDAPAAAYDWTNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDVVEGDFFEPLP 
           ____________________145_________________________________________________________________________________________________ 

           ______________________________________283_______________________309___________________________________________           
 1tw2(B) : RKADAIILSFVLLNWPDHDAVRILTRCAEALEPGGRILIHERDDLHENSFNEQFTELDLRMLVFLGGALRTREKWDGLAASAGLVVEEVRQLPSPTIPYDLSLLVLAPAA           
         :                                                                                                                          
 1tw3(A) : RKADAIILSFVLLNWPDHDAVRILTRCAEALEPGGRILIHERDDLHENSFNEQFTELDLRMLVFLGGALRTREKWDGLAASAGLVVEEVRQLPSPTIPYDLSLLVLAPA*           
           ______________________________________283_______________________309___________________________________________           

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
10.7
Translation
(A)
-0.2
Closure
(%)
97.9
Bending Residues
( green )
  145 - 146
  283 - 287
  309 - 315
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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