Cleavage And Polyadenylation Specificity Factor 73 Kda Subunit

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Cleavage And Polyadenylation Specificity Factor 73 Kda Subunit
  Conformer 1
(PDB)
2i7v (A)
  Conformer 2
(PDB)
2i7t (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 264 0.96   11 - 212   239 - 246   358 - 361   394 - 457
2 136 0.38   213 - 238   247 - 357   362 - 393

Sequence


           ________________________________________________________________________________________________________________________ 
 2i7v(A) : EESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKlYTETDLEESMDKI 
         :                                                                                                                          
 2i7t(A) : **SDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKlYTETDLEESMDKI 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________210_________________________238_____246_________ 
 2i7v(A) : ETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDE 
         :                                                                                                                          
 2i7t(A) : ETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQ-----mAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDE 
           ________________________________________________________________________210_________________________238_____246_________ 

           _______________________________________________________________________________________356__361_________________________ 
 2i7v(A) : YWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAnNPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKM 
         :                                                                                                                          
 2i7t(A) : YWQNHPELHDIPIYYA----------------------fKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKM 
           _______________________________________________________________________________________356__361_________________________ 

           ____393__________________________________________________________________                                                
 2i7v(A) : SVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFR                                                
         :                                                                                                                          
 2i7t(A) : SVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFR                                                
           ____393__________________________________________________________________                                                

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
6.9
Translation
(A)
-0.6
Closure
(%)
79.9
Bending Residues
( green )
  210 - 217
  238 - 239
  246 - 250
  356 - 358
  361 - 362
  393 - 394
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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