Cyclin-Dependent Kinase 6

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Cyclin-Dependent Kinase 6
  Conformer 1
(PDB)
1bi7 (A)
  Conformer 2
(PDB)
1g3n (A)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 204 1.39   19 - 20   77 - 79   98 - 296
2 55 1.56   15 - 18   21 - 76   80 - 97

Sequence


           ________18________________________________________________________76_79________________97_______________________________ 
 1bi7(A) : *DQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQ-----------------------eHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQ 
         :                                                                                                                          
 1g3n(A) : ADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQ 
           ________18________________________________________________________76_79________________97_______________________________ 

           ________________________________________________________________________________________________________________________ 
 1bi7(A) : LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 
         :                                                                                                                          
 1g3n(A) : LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 
           ________________________________________________________________________________________________________________________ 

           _____________________________________________________                                                                    
 1bi7(A) : LPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQ                                                                    
         :                                                                                                                          
 1g3n(A) : LPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQ                                                                    
           _____________________________________________________                                                                    

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
13.1
Translation
(A)
-1.1
Closure
(%)
4.1
Bending Residues
( green )
  18 - 23
  76 - 77
  79 - 80
  97 - 98
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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