E8 Antibody

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name E8 Antibody
  Conformer 1
(PDB)
1wej (H)
  Conformer 2
(PDB)
1qbl (H)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 161 0.62   3 - 127   145 - 150   152 - 155   164 - 165   167 - 182   205 - 212
2 51 0.67   128 - 144   151 - 151   156 - 163   166 - 166   183 - 204   213 - 214

Sequence


           ________________________________________________________________________________________________________________________ 
 1wej(H) : EVQLQQSGAELVKPGASVKLSCTASGFNIKDTYMHWVKQRPEKGLEWIGRIDPASGNTKYDPKFQDKATITADTSSNTAYLQLSSLTSEDTAVYYCAGYDYGNFDYWGQGTTLTVSSAET 
         :                                                                                                                          
 1qbl(H) : EVQLQQSGAELVKPGASVKLSCTASGFNIKDTYMHWVKQRPEKGLEWIGRIDPASGNTKYDPKFQDKATITADTSSNTAYLQLSSLTSEDTAVYYCAGYDYGNFDYWGQGTTLTVSSAET 
           ________________________________________________________________________________________________________________________ 

           ____127______________144__149___155____162_________________182___________________204_____212___________                  
 1wej(H) : TPPSVYPLAPGTAALKSSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLTSSVTVPSSTWPSQTVTCNVAHPASSTKVDKKIVPRNCGGDC                  
         :                                                                                                                          
 1qbl(H) : TPPSVYPLAPGTAALKSSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLTSSVTVPSSTWPSQTVTCNVAHPASSTKVDKKIVPRNC****                  
           ____127______________144__149___155____162_________________182___________________204_____212___________                  

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
11.8
Translation
(A)
0.1
Closure
(%)
63.5
Bending Residues
( green )
  127 - 128
  144 - 145
  149 - 152
  155 - 156
  162 - 167
  182 - 183
  204 - 206
  212 - 213
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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