Erythropoietin Receptor

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Erythropoietin Receptor
  Conformer 1
(PDB)
1ern (B)
  Conformer 2
(PDB)
1eba (A)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 99 1.66   30 - 35   120 - 205   210 - 219
2 93 0.89   25 - 29   36 - 119   206 - 209

Sequence


           __________________29____35_________________________________________________________________________________119__________ 
 1ern(B) : KFESKAALLAA---eELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVA 
         :                                                                                                                          
 1eba(A) : KFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVA 
           __________________29____35_________________________________________________________________________________119__________ 

           ________________________________________________________________________205_209_______________                           
 1ern(B) : RLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGgAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPS**                           
         :                                                                                                                          
 1eba(A) : RLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGg--SVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSDL                           
           ________________________________________________________________________205_209_______________                           

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
13.0
Translation
(A)
0.2
Closure
(%)
61.2
Bending Residues
( green )
  29 - 30
  35 - 36
  119 - 120
  205 - 206
  209 - 210
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Mixed

PyMOL Script

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