Immunoglobulin Gamma-1 Heavy Chain Constant Region

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Immunoglobulin Gamma-1 Heavy Chain Constant Region
  Conformer 1
(PDB)
1e4k (B)
  Conformer 2
(PDB)
2iwg (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 102 0.69   340 - 441
2 99 2.07   241 - 339

Sequence


           ____________________________________________________________________________________________________________339_________ 
 1e4k(B) : CPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPQVKFNWYVDGVQVHNAKTKPREQQYNSTYRVVSVLTVLHQNWLDGKEYKCKVSNKALPAPIEKTISKAKGQPREPQV 
         :                                                                                                                          
 2iwg(A) : ********GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQV 
           ____________________________________________________________________________________________________________339_________ 

           ________________________________________________________________________________________________                         
 1e4k(B) : YTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLS                         
         :                                                                                                                          
 2iwg(A) : YTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSL*                         
           ________________________________________________________________________________________________                         

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
25.0
Translation
(A)
1.2
Closure
(%)
37.1
Bending Residues
( green )
  339 - 342
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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