Hexokinase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Hexokinase
  Conformer 1
(PDB) 		2e2q (A)
  Conformer 2
(PDB) 		2e2n (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 24 0.4   99 - 111   122 - 129   273 - 275
2 116 0.3   3 - 98   276 - 295
3 153 0.32   112 - 121   130 - 272

Sequence


           _______________________________________________________________________________________________97___________111_______12 
 2e2q(A) : MMIIVGVDAGGTKTKAVAYDCEGNFIGEGSSGPGNYHNVGLTRAIENIKEAVKIAAKGEADVVGMGVAGLDSKFDWENFTPLASLIAPKVIIQHDGVIALFAETLGEPGVVVIAGTGSVV 
         :                                                                                                                          
 2e2n(A) : MMIIVGVDAGGTKTKAVAYDCEGNFIGEGSSGPGNYHNVGLTRAIENIKEAVKIAAKGEADVVGMGVAGLDSKFDWENFTPLASLIAPKVIIQHDGVIALFAETLGEPGVVVIAGTGSVV 
           _______________________________________________________________________________________________97___________111_______12 

           1_____129_______________________________________________________________________________________________________________ 
 2e2q(A) : EGYNGKEFLRVGGRGWLLSDDGSAYWVGRKALRKVLKMMDGLENKTILYNKVLKTINVKDLDELVMWSYTSSCQIDLVASIAKAVDEAANEGDTVAMDILKQGAELLASQAVYLARKIGT 
         :                                                                                                                          
 2e2n(A) : EGYNGKEFLRVGGRGWLLSDDGSAYWVGRKALRKVLKMMDGLENKTILYNKVLKTINVKDLDELVMWSYTSSCQIDLVASIAKAVDEAANEGDTVAMDILKQGAELLASQAVYLARKIGT 
           1_____129_______________________________________________________________________________________________________________ 

           ______________________________273_________________________                                                               
 2e2q(A) : NKVYLKGGMFRSNIYHKFFTLYLEKEGIISDLGKRSPEIGAVILAYKEVGCDIKKLI*                                                               
         :                                                                                                                          
 2e2n(A) : NKVYLKGGMFRSNIYHKFFTLYLEKEGIISDLGKRSPEIGAVILAYKEVGCDIKKLIS                                                               
           ______________________________273_________________________                                                               

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		18.3
Translation
(A) 		0.2
Closure
(%) 		82.6
Bending Residues
( green ) 		  97 - 99
  273 - 278
Bending Region Analysis
Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( yellow ) 		3
Rotation Angle
(deg) 		10.5
Translation
(A) 		0.3
Closure
(%) 		100.0
Bending Residues
( green ) 		  111 - 115
  121 - 122
  129 - 132
  271 - 275
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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