Hst2 Protein

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Hst2 Protein
  Conformer 1
(PDB)
1q14 (A)
  Conformer 2
(PDB)
1szd (A)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 201 1.35   8 - 64   83 - 139   182 - 290
2 60 0.83   65 - 82   140 - 181

Sequence


           ________________________________________________________________62__________________82__________________________________ 
 1q14(A) : GMASMSVSTASTEMSVRKIAAHMKSNPNAKVIFMVGAGISTSCG--------------lARLKLPYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQN 
         :                                                                                                                          
 1szd(A) : *MASMSVSTASTEMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQN 
           ________________________________________________________________62__________________82__________________________________ 

           ____________________139_______________________________________181_______________________________________________________ 
 1q14(A) : IDTLERQAGVKDDLIIEAHGSFAHCHCIGCGKVYPPQVFKSKLAEHPIKDFVKCDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREK---qQPLVIVVGTSLAVYPFASLPEEIPRK 
         :                                                                                                                          
 1szd(A) : IDTLERQAGVKDDLIIEAHGSFAHCHCIGCGKVYPPQVFKSKLAEHPIKDFVKCDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREKITTqQPLVIVVGTSLAVYPFASLPEEIPRK 
           ____________________139_______________________________________181_______________________________________________________ 

           __________________________________________________________________                                                       
 1q14(A) : VKRVLCNLETVGDFKANKRPTDLIVHQYSDEFAEQLVEELGWQEDFEKILTAQkEQLLEIVHDLEN                                                       
         :                                                                                                                          
 1szd(A) : VKRVLCNLETVGDFKANKRPTDLIVHQYSDEFAEQLVEELGWQEDFEKILTA**************                                                       
           __________________________________________________________________                                                       

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
15.4
Translation
(A)
0.8
Closure
(%)
96.7
Bending Residues
( green )
  62 - 66
  82 - 83
  139 - 142
  181 - 182
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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