3-Hydroxyisobutyrate Dehydrogenase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name 3-Hydroxyisobutyrate Dehydrogenase
  Conformer 1
(PDB)
2cvz (C)
  Conformer 2
(PDB)
2cvz (D)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 158 0.28   4 - 164
2 121 0.2   165 - 287

Sequence


           ________________________________________________________________________________________________________________________ 
 2cvz(C) : EKVAFIGLGAgYPaGHLARRFPTLVWNRTFEKALRHQEEFGSEAVPLERVAEARVIFTCLPTTREVYEVAEALYPYLREGTYWVDATSGEPEASRRLAERLREKGVTYLDAPVSGGTSGA 
         :                                                                                                                          
 2cvz(D) : EKVAFIGLGAgYPaGHLARRFPTLVWNRTFEKALRHQEEFGSEAVPLERVAEARVIFTCLPTTREVYEVAEALYPYLREGTYWVDATSGEPEASRRLAERLREKGVTYLDAPVSGGTSGA 
           ________________________________________________________________________________________________________________________ 

           __________________________________161___________________________________________________________________________________ 
 2cvz(C) : EAGTLTVlGGPEEAVERVRPFLAYAKKVVHVGPVGAGHAVKAINNALLAVNLWAAGEGLLALVKQGVSAEKALEVINASSGRSNATENLIPQRVLTRAFPKTFALGLLVKDLGIAgVLDG 
         :                                                                                                                          
 2cvz(D) : EAGTLTVlGGPEEAVERVRPFLAYAKKVVHVGPVGAGHAVKAINNALLAVNLWAAGEGLLALVKQGVSAEKALEVINASSGRSNATENLIPQRVLTRAFPKTFALGLLVKDLGIAgVLDG 
           __________________________________161___________________________________________________________________________________ 

           ___________________________________________                                                                              
 2cvz(C) : EKAPSPLLRLAREVYEaKRELGPDADHVEALRLLERWGGVEIR                                                                              
         :                                                                                                                          
 2cvz(D) : EKAPSPLLRLAREVYEaKRELGPDADHVEALRLLERWGGVEIR                                                                              
           ___________________________________________                                                                              

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
12.5
Translation
(A)
-0.5
Closure
(%)
96.2
Bending Residues
( green )
  161 - 166
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

Download and extract PyMOL PML script file Download