4-Hydroxythreonine-4-Phosphate Dehydrogenase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name 4-Hydroxythreonine-4-Phosphate Dehydrogenase
  Conformer 1
(PDB)
1ptm (B)
  Conformer 2
(PDB)
1r8k (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 192 0.68   5 - 148   277 - 326
2 124 0.63   149 - 276   327 - 327

Sequence


           ________________________________________________________________________________________________________________________ 
 1ptm(B) : VKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTNRAAlGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRAPVTAGQLAVENGHYVVETLARACDGCLNGEFAALITGPVH 
         :                                                                                                                          
 1r8k(A) : *SAQRVVITPGEPAGSGPDLVVQLAQRAWPIELVVCADGALLTERAAlGLPLSLLPYSPDVPAAPQPAGTLTLLPVSLRAPAISGQLTVENGPYVVETLARACDGCLNGEFAALITGPVH 
           ________________________________________________________________________________________________________________________ 

           _______________________148______________________________________________________________________________________________ 
 1ptm(B) : KGVINDAGIPFTGHTEFFEERSQAKKVVlATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHgTEEIDTIIPVLNELRAQGkLNGPLPA 
         :                                                                                                                          
 1r8k(A) : KGVINDAGISFTGHTEFFEERSQAKKVVlATEELRVALATTHLPLRAIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHgTEEIDTIIPVLDELRAQGkLNGPLPA 
           _______________________148______________________________________________________________________________________________ 

           ________________________274_______________________________________________325____                                        
 1ptm(B) : DTLFQPKYLDNADAVLAyHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKiVNTQ                                        
         :                                                                                                                          
 1r8k(A) : DTLFQPKYLDNADAVLAyHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKiVNTQ                                        
           ________________________274_______________________________________________325____                                        

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
16.3
Translation
(A)
-0.3
Closure
(%)
54.5
Bending Residues
( green )
  148 - 150
  274 - 278
  325 - 327
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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