Hypoxanthine-Guanine Phosphoribosyltransferase

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Hypoxanthine-Guanine Phosphoribosyltransferase
  Conformer 1
(PDB) 		1bzy (C)
  Conformer 2
(PDB) 		1z7g (C)
  Window Length 15
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 91 0.76   11 - 61   75 - 82   179 - 210
2 80 2.19   62 - 74   102 - 178

Sequence


           ________________________________________________________61___________74_________________________________________________ 
 1bzy(C) : SPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLST 
         :                                                                                                                          
 1z7g(C) : SPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLK----------iKVIGGDDLST 
           ________________________________________________________61___________74_________________________________________________ 

           ____________________________________________________178_______________________________________                           
 1bzy(C) : LTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA                           
         :                                                                                                                          
 1z7g(C) : LTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA                           
           ____________________________________________________178_______________________________________                           

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		16.6
Translation
(A) 		0.1
Closure
(%) 		100.0
Bending Residues
( green ) 		  61 - 62
  74 - 119
  178 - 179
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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