Immunoglobulin Gamma-1 Heavy Chain Constant Region

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Immunoglobulin Gamma-1 Heavy Chain Constant Region
  Conformer 1
(PDB)
1oqx (B)
  Conformer 2
(PDB)
1adq (A)
  Window Length 15
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 169 1.06   245 - 283   307 - 436
2 23 2.58   284 - 306

Sequence


           ____________________________________274_____________________________306_________________________________________________ 
 1oqx(B) : GGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSR 
         :                                                                                                                          
 1adq(A) : **PSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPQVQFNWYVDGVQVHNAKTKPREQQFNSTYRVVSVLTVLHQNWLDGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQ 
           ____________________________________274_____________________________306_________________________________________________ 

           _________________________________________________________________________________________                                
 1oqx(B) : DELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLS                                
         :                                                                                                                          
 1adq(A) : EEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSL*                                
           _________________________________________________________________________________________                                

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
22.3
Translation
(A)
-0.1
Closure
(%)
5.6
Bending Residues
( green )
  274 - 284
  306 - 307
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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