Importin Beta-1

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Importin Beta-1
  Conformer 1
(PDB)
1gcj (A)
  Conformer 2
(PDB)
1m5n (S)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 369 1.31   38 - 58   75 - 80   91 - 106   112 - 449
2 63 1.43   6 - 37   59 - 74   81 - 90   107 - 111

Sequence


           ________________________________________37___________________58______________74____80________90_____________106__111____ 
 1gcj(A) : PDYASGeLITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAG 
         :                                                                                                                          
 1m5n(S) : *****MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAG 
           ________________________________________37___________________58______________74____80________90_____________106__111____ 

           ________________________________________________________________________________________________________________________ 
 1gcj(A) : IACAEIPVSQWPELIPQLVANVTNPNSTEH-kESTLEAIGYICQDIDPEQLQDKSNEILTAIIQG-rKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFI-qVVCEATQCPDTRVRV 
         :                                                                                                                          
 1m5n(S) : IACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRV 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1gcj(A) : AALQNLVKI-sLYYQY-eTY-gPALFAITIEA-kSDIDEVALQGIEFWSNVCDEE-dLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCL-lL 
         :                                                                                                                          
 1m5n(S) : AALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLL 
           ________________________________________________________________________________________________________________________ 

           ________________________________________________________________________________________________________________________ 
 1gcj(A) : STCCEDDIVPHVLPFIKEHIKNPDWRYRDAAV-aFGSILEGPEPNQLKPLVIQA-pTLIEL-kDPSVVVRDTTAWTVGRICELLPEAAINDVYLVPNSS********************* 
         :                                                                                                                          
 1m5n(S) : ATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFS 
           ________________________________________________________________________________________________________________________ 

           __________                                                                                                               
 1gcj(A) : **********                                                                                                               
         :                                                                                                                          
 1m5n(S) : SLAEAAYEAA                                                                                                               
           __________                                                                                                               

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
9.3
Translation
(A)
-0.2
Closure
(%)
97.3
Bending Residues
( green )
  37 - 38
  58 - 59
  74 - 75
  80 - 81
  90 - 91
  106 - 107
  111 - 112
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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