Major Prion Protein

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Major Prion Protein
  Conformer 1
(PDB)
1i4m (A)
  Conformer 2
(PDB)
1uw3 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)
Residues
1 66 1.58   127 - 192
2 32 2.09   193 - 224

Sequence


           ____________________________________________________________________189_________________________________________         
 1i4m(A) : GAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYY****         
         :                                                                                                                          
 1uw3(A) : ******LGGYMLGSAMSRPLIHFGNDYEDCYYRENMHRYPNQVYYRPVDQYSNQNNFVHDCVNITVKQHTVTTTTKGENFTETDIKIMERVVEQMCITQYQRESQAYYQRGA         
           ____________________________________________________________________189_________________________________________         

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property Value
Fixed Domain
( blue )
1
Moving Domain
( red )
2
Rotation Angle
(deg)
174.4
Translation
(A)
1.1
Closure
(%)
99.7
Bending Residues
( green )
  189 - 195
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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