DynDom - Protein Domain Motions

Bifunctional Protein Puta

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Bifunctional Protein Puta
Conformer 1 (PDB)	6x9a (A)
Conformer 2 (PDB)	6x9a (B)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	660	0.38	21 - 156 158 - 159 165 - 538 549 - 565 572 - 576 591 - 591 594 - 594 601 - 603 642 - 642 646 - 647 652 - 655 657 - 657 661 - 661 663 - 669 673 - 676 810 - 813 815 - 815 822 - 836 842 - 845 849 - 851 856 - 857 861 - 863 870 - 884 910 - 925 952 - 957 966 - 966 971 - 973 985 - 988 990 - 994 996 - 996 999 - 999 1004 - 1008 1015 - 1015 1083 - 1085 1088 - 1092 1217 - 1217 1223 - 1231
2	549	0.43	16 - 20 157 - 157 160 - 164 539 - 548 566 - 571 577 - 590 592 - 593 595 - 600 604 - 641 643 - 645 648 - 651 656 - 656 658 - 660 662 - 662 670 - 672 677 - 809 814 - 814 816 - 821 837 - 841 846 - 848 852 - 855 858 - 860 864 - 869 885 - 909 926 - 951 958 - 965 967 - 970 974 - 984 989 - 989 995 - 995 997 - 998 1000 - 1003 1009 - 1014 1016 - 1082 1086 - 1087 1093 - 1216 1218 - 1222

Sequence

`_____20_________________________________________________________________________________________________________________` `6x9a(A) : APAPFADFAPPVRPQSTLRRAITAAYRRPETECLPPLVEAATQSKEIRDAAASTARKLIEALRGKgVEGLVQEYSLSSQEGVALMCLAEALLRIPDTATRDALIRDKIADGNWKSHLsRS` `:` `6x9a(B) : APAPFADFAPPVRPQSTLRRAITAAYRRPETECLPPLVEAATQSKEIRDAAASTARKLIEALRGKgVEGLVQEYSLSSQEGVALMCLAEALLRIPDTATRDALIRDKIADGNWKSHL-rS` `_____20_________________________________________________________________________________________________________________` `______________156_____164_______________________________________________________________________________________________` `6x9a(A) : LFVNAATWGLVVTGKLTSTVNDRSLAAALTRLISRCGEPVIRRGVDMAMRMMGEQFVTGETIREALKRSKELEEKGFSYSYDMLGEAATTAADAERYYRDYESAIHAIGKASAGRGIYEG` `:` `6x9a(B) : LFVNAATWGLVVTGKLTSTVNDRSLAAALTRLISRCGEPVIRRGVDMAMRMMGEQFVTGETIREALKRSKELEEKGFSYSYDMLGEAATTAADAERYYRDYESAIHAIGKASAGRGIYEG` `______________156_____164_______________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6x9a(A) : PGISIKLSALHPRYSRAQAARVMGELLPRVKALALLAKNYDIGLNIDAEEADRLELSLDLLEVLCLDGDLSGWNGMGFVVQAYGKRCPFVLDFIIDLARRSGRRIMVRLVKGAYWDAEIK` `:` `6x9a(B) : PGISIKLSALHPRYSRAQAARVMGELLPRVKALALLAKNYDIGLNIDAEEADRLELSLDLLEVLCLDGDLSGWNGMGFVVQAYGKRCPFVLDFIIDLARRSGRRIMVRLVKGAYWDAEIK` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6x9a(A) : RAQLDGLADFPVFTRKIHTDVSYIACAAKLLAATDVVFPQFATHNAQTLAAIYHMAGKDFHVGKYEFQCLHGMGEPLYEEVVGRGKLDRPCRIYAPVGTHETLLAYLVRRLLENGANSSF` `:` `6x9a(B) : RAQLDGLADFPVFTRKIHTDVSYIACAAKLLAATDVVFPQFATHNAQTLAAIYHMAGKDFHVGKYEFQCLHGMGEPLYEEVVGRGKLDRPCRIYAPVGTHETLLAYLVRRLLENGANSSF` `________________________________________________________________________________________________________________________` `____________________________________538_______548______________565__570_________________590_______600___________________` `6x9a(A) : VHRINDPKVSIDELIADPVEVVRAMPVVGAKHDRIALPAELFGDARTNSAGLDLSNEETLASLTEALRESAAMKWTALPQLATGPAAGETRTVLNPGDHRDVVGSVTETSEEDARRAVRL` `:` `6x9a(B) : VHRINDPKVSIDELIADPVEVVRAMPVVGAKHDRIALPAELFGDARTNSAGLDLSNEETLASLTEALRESAAMKWTALPQLATGPAAGETRTVLNPGDHRDVVGSVTETSEEDARRAVRL` `____________________________________538_______548______________565__570_________________590_______600___________________` `___________________641_645___651_655__660______669____676_______________________________________________________________` `6x9a(A) : AADAAPDWAAVPPSERAACLDRAAELMQARMPTLLGLIIREAGKSALNAIAEVREAIDFLRYYAEQTRRTLGPGHGPLGPIVCISPWNFPLAIFTGQIAAALVAGNPVLAKPAEETPLIA` `:` `6x9a(B) : AADAAPDWAAVPPSERAACLDRAAELMQARMPTLLGLIIREAGKSALNAIAEVREAIDFLRYYAEQTRRTLGPGHGPLGPIVCISPWNFPLAIFTGQIAAALVAGNPVLAKPAEETPLIA` `___________________641_645___651_655__660______669____676_______________________________________________________________` `___________________________________________________________________809_________821____________836__841_845___851_855__86` `6x9a(A) : AEGVRILREAGIPASALQLLPGDGRVGAALVAAAETAGVMFTGSTEVARLIQAQLADRLSPAGRPIPLIAETGGQNAMIVDSSALAEQVVGDVITSAFDSAGQRCSALRVLCLQEDVADR` `:` `6x9a(B) : AEGVRILREAGIPASALQLLPGDGRVGAALVAAAETAGVMFTGSTEVARLIQAQLADRLSPAGRPIPLIAETGGQNAMIVDSSALAEQVVGDVITSAFDSAGQRCSALRVLCLQEDVADR` `___________________________________________________________________809_________821____________836__841_845___851_855__86` `0______869____________884______________________909_____________925_______________________951___957_____965__970_________` `6x9a(A) : ILTMLKGALHELHIGRTDRLSVDVGPVITSEAKDNIEKHIERMRGLGRKVEQIGLASETGVGTFVPPTIIELEKLSDLQREVFGPVLHVIRYRRDDLDRLVDDVNATGYGLTFGLHTRLD` `:` `6x9a(B) : ILTMLKGALHELHIGRTDRLSVDVGPVITSEAKDNIEKHIERMRGLGRKVEQIGLASETGVGTFVPPTIIELEKLSDLQREVFGPVLHVIRYRRDDLDRLVDDVNATGYGLTFGLHTRLD` `0______869____________884______________________909_____________925_______________________951___957_____965__970_________` `__984_988___994_____1003_1008__1014________________________________________________________________1082______1092_______` `6x9a(A) : ETIAHVTSRIKAGNLYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVTTAPVPPQHSSVHTDPVLLDFAKWLDGKGARAEAEAARNAGSSSALGLDLELPGPVGERNLYTLHAR` `:` `6x9a(B) : ETIAHVTSRIKAGNLYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVTTAPVPPQHSSVHTDPVLLDFAKWLDGKGARAEAEAARNAGSSSALGLDLELPGPVGERNLYTLHAR` `__984_988___994_____1003_1008__1014________________________________________________________________1082______1092_______` `_________________________________________________________________________________________________________________1216__1` `6x9a(A) : GRILLVPATESGLYHQLAAALATGNSVAIDAASGLQASLKNLPQTVGLRVSWSKDWAADGPFAGALVEGDAERIRAVNKAIAALPGPLLLVQAASSGEIARNPDAYCLNWLVEEVSASIN` `:` `6x9a(B) : GRILLVPATESGLYHQLAAALATGNSVAIDAASGLQASLKNLPQTVGLRVSWSKDWAADGPFAGALVEGDAERIRAVNKAIAALPGPLLLVQAASSGEIARNPDAYCLNWLVEEVSASIN` `_________________________________________________________________________________________________________________1216__1` `222___________` `6x9a(A) : TAAAGGNASLMAIG` `:` `6x9a(B) : TAAAGGNASLMAIG` `222___________`

Morph

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Status: Initialising

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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	2.8
Translation (A)	0.1
Closure (%)	72.9
Bending Residues ( green )	20 - 21 156 - 160 164 - 165 538 - 539 548 - 549 565 - 566 570 - 577 590 - 595 600 - 601 603 - 604 641 - 643 645 - 649 651 - 653 655 - 658 660 - 663 669 - 670 672 - 673 676 - 677 809 - 816 821 - 822 836 - 837 841 - 842 845 - 846 848 - 849 851 - 852 855 - 858 860 - 864 869 - 870 884 - 885 909 - 910 925 - 926 951 - 952 957 - 958 965 - 967 970 - 971 973 - 974 984 - 985 988 - 990 994 - 1000 1003 - 1004 1008 - 1009 1014 - 1016 1082 - 1083 1085 - 1088 1092 - 1093 1216 - 1218 1222 - 1223
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

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