DynDom - Protein Domain Motions

Bifunctional Protein Puta

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Bifunctional Protein Puta
Conformer 1 (PDB)	6x99 (A)
Conformer 2 (PDB)	6x99 (B)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	860	0.45	16 - 539 548 - 577 591 - 591 593 - 603 623 - 629 634 - 635 640 - 640 642 - 678 681 - 682 687 - 687 695 - 698 704 - 712 716 - 722 724 - 724 739 - 739 741 - 741 746 - 752 754 - 755 776 - 778 810 - 837 841 - 884 904 - 926 937 - 939 942 - 944 951 - 1009 1014 - 1034 1036 - 1039 1082 - 1093 1214 - 1231
2	350	0.42	540 - 547 578 - 590 592 - 592 604 - 622 630 - 633 636 - 639 641 - 641 679 - 680 683 - 686 688 - 694 699 - 703 713 - 715 723 - 723 725 - 738 740 - 740 742 - 745 753 - 753 756 - 775 779 - 809 838 - 840 885 - 903 927 - 936 940 - 941 945 - 950 1010 - 1013 1035 - 1035 1040 - 1081 1094 - 1213

Sequence

`________________________________________________________________________________________________________________________` `6x99(A) : APAPFADFAPPVRPQSTLRRAITAAYRRPETECLPPLVEAATQSKEIRDAAASTARKLIEALRGKgSGVEGLVQEYSLSSQEGVALMCLAEALLRIPDTATRDALIRDKIADGNWKSHLs` `:` `6x99(B) : APAPFADFAPPVRPQSTLRRAITAAYRRPETECLPPLVEAATQSKEIRDAAASTARKLIEALRGKg--VEGLVQEYSLSSQEGVALMCLAEALLRIPDTATRDALIRDKIADGNWKSHLs` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6x99(A) : RSLFVNAATWGLVVTGKLTSTVNDRSLAAALTRLISRCGEPVIRRGVDMAMRMMGEQFVTGETIREALKRSKELEEKGFSYSYDMLGEAATTAADAERYYRDYESAIHAIGKASAGRGIY` `:` `6x99(B) : RSLFVNAATWGLVVTGKLTSTVNDRSLAAALTRLISRCGEPVIRRGVDMAMRMMGEQFVTGETIREALKRSKELEEKGFSYSYDMLGEAATTAADAERYYRDYESAIHAIGKASAGRGIY` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6x99(A) : EGPGISIKLSALHPRYSRAQAARVMGELLPRVKALALLAKNYDIGLNIDAEEADRLELSLDLLEVLCLDGDLSGWNGMGFVVQAYGKRCPFVLDFIIDLARRSGRRIMVRLVKGAYWDAE` `:` `6x99(B) : EGPGISIKLSALHPRYSRAQAARVMGELLPRVKALALLAKNYDIGLNIDAEEADRLELSLDLLEVLCLDGDLSGWNGMGFVVQAYGKRCPFVLDFIIDLARRSGRRIMVRLVKGAYWDAE` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `6x99(A) : IKRAQLDGLADFPVFTRKIHTDVSYIACAAKLLAATDVVFPQFATHNAQTLAAIYHMAGKDFHVGKYEFQCLHGMGEPLYEEVVGRGKLDRPCRIYAPVGTHETLLAYLVRRLLENGANS` `:` `6x99(B) : IKRAQLDGLADFPVFTRKIHTDVSYIACAAKLLAATDVVFPQFATHNAQTLAAIYHMAGKDFHVGKYEFQCLHGMGEPLYEEVVGRGKLDRPCRIYAPVGTHETLLAYLVRRLLENGANS` `________________________________________________________________________________________________________________________` `_______________________________________539_____547___________________________577__________590__________603______________` `6x99(A) : SFVHRINDPKVSIDELIADPVEVVRAMPVVGAKHDRIALPAELFGDARTNSAGLDLSNEETLASLTEALRESAAMKWTALPQLATGPAAGETRTVLNPGDHRDVVGSVTETSEEDARRAV` `:` `6x99(B) : SFVHRINDPKVSIDELIADPVEVVRAMPVVGAKHDRIALPAELFGDARTNSAGLDLSNEETLASLTEALRESAAMKWTALPQLATGPAAGETRTVLNPGDHRDVVGSVTETSEEDARRAV` `_______________________________________539_____547___________________________577__________590__________603______________` `__622____629_633___639____________________________________678_____686_____694_698__703______712_______722_____________73` `6x99(A) : RLAADAAPDWAAVPPSERAACLDRAAELMQARMPTLLGLIIREAGKSALNAIAEVREAIDFLRYYAEQTRRTLGPGHGPLGPIVCISPWNFPLAIFTGQIAAALVAGNPVLAKPAEETPL` `:` `6x99(B) : RLAADAAPDWAAVPPSERAACLDRAAELMQARMPTLLGLIIREAGKSALNAIAEVREAIDFLRYYAEQTRRTLGPGHGPLGPIVCISPWNFPLAIFTGQIAAALVAGNPVLAKPAEETPL` `__622____629_633___639____________________________________678_____686_____694_698__703______712_______722_____________73` `8____745____752____________________775_______________________________809_________________________837____________________` `6x99(A) : IAAEGVRILREAGIPASALQLLPGDGRVGAALVAAAETAGVMFTGSTEVARLIQAQLADRLSPAGRPIPLIAETGGQNAMIVDSSALAEQVVGDVITSAFDSAGQRCSALRVLCLQEDVA` `:` `6x99(B) : IAAEGVRILREAGIPASALQLLPGDGRVGAALVAAAETAGVMFTGSTEVARLIQAQLADRLSPAGRPIPLIAETGGQNAMIVDSSALAEQVVGDVITSAFDSAGQRCSALRVLCLQEDVA` `8____745____752____________________775_______________________________809_________________________837____________________` `________________________884________________903____________________926_______936_____944___950___________________________` `6x99(A) : DRILTMLKGALHELHIGRTDRLSVDVGPVITSEAKDNIEKHIERMRGLGRKVEQIGLASETGVGTFVPPTIIELEKLSDLQREVFGPVLHVIRYRRDDLDRLVDDVNATGYGLTFGLHTR` `:` `6x99(B) : DRILTMLKGALHELHIGRTDRLSVDVGPVITSEAKDNIEKHIERMRGLGRKVEQIGLASETGVGTFVPPTIIELEKLSDLQREVFGPVLHVIRYRRDDLDRLVDDVNATGYGLTFGLHTR` `________________________884________________903____________________926_______936_____944___950___________________________` `____________________________1009_____________________1034_1039______________________________________1081________1093____` `6x99(A) : LDETIAHVTSRIKAGNLYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVTTAPVPPQHSSVHTDPVLLDFAKWLDGKGARAEAEAARNAGSSSALGLDLELPGPVGERNLYTLH` `:` `6x99(B) : LDETIAHVTSRIKAGNLYINRNIIGAVVGVQPFGGRGLSGTGPKAGGPLYLGRLVTTAPVPPQHSSVHTDPVLLDFAKWLDGKGARAEAEAARNAGSSSALGLDLELPGPVGERNLYTLH` `____________________________1009_____________________1034_1039______________________________________1081________1093____` `________________________________________________________________________________________________________________1213____` `6x99(A) : ARGRILLVPATESGLYHQLAAALATGNSVAIDAASGLQASLKNLPQTVGLRVSWSKDWAADGPFAGALVEGDAERIRAVNKAIAALPGPLLLVQAASSGEIARNPDAYCLNWLVEEVSAS` `:` `6x99(B) : ARGRILLVPATESGLYHQLAAALATGNSVAIDAASGLQASLKNLPQTVGLRVSWSKDWAADGPFAGALVEGDAERIRAVNKAIAALPGPLLLVQAASSGEIARNPDAYCLNWLVEEVSAS` `________________________________________________________________________________________________________________1213____` `________________` `6x99(A) : INTAAAGGNASLMAIG` `:` `6x99(B) : INTAAAGGNASLMAIG` `________________`

Morph

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Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	2.6
Translation (A)	0.1
Closure (%)	69.1
Bending Residues ( green )	539 - 540 547 - 548 577 - 578 590 - 593 603 - 604 622 - 623 629 - 630 633 - 636 639 - 642 678 - 683 686 - 688 694 - 695 698 - 699 703 - 704 712 - 713 715 - 716 722 - 725 738 - 742 745 - 746 752 - 756 775 - 776 778 - 779 809 - 810 837 - 838 840 - 841 884 - 885 903 - 906 926 - 927 936 - 937 939 - 942 944 - 945 950 - 951 1009 - 1010 1013 - 1014 1034 - 1036 1039 - 1040 1081 - 1082 1093 - 1094 1213 - 1214
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

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