Endothelin Receptor Subtype-B

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Endothelin Receptor Subtype-B
  Conformer 1
(PDB) 		5gli (A)
  Conformer 2
(PDB) 		5glh (A)
  Window Length 7
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 275 2.26   91 - 300   1021 - 1033   330 - 396
2 115 1.58   301 - 1009   1034 - 329

Sequence


           ________________________________________________________________________________________________________________________ 
 5gli(A) : ISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLYIIYKNKCMRNGPNILIASLALGDLLHIVIAIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVA 
         :                                                                                                                          
 5glh(A) : ***PPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLYIIYK-----NgPNILIASLALGDLLHIVIAIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVA 
           ________________________________________________________________________________________________________________________ 

           _____________________________________________________________________________________________300_______1009_____________ 
 5gli(A) : SWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYATAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKNIFEMLRIDEG---------- 
         :                                                                                                                          
 5glh(A) : SW----------wTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYATAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKNIFEMLRIDEGLRLKIYKDTE 
           _____________________________________________________________________________________________300_______1009_____________ 

           __________________________________________________1033__________________________________________________________________ 
 5gli(A) : G----GSGG-----------------------------DEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQT 
         :                                                                                                                          
 5glh(A) : GYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQT 
           __________________________________________________1076__________________________________________________________________ 

           _____________1116_______________________________________________________________________________________________         
 5gli(A) : PNRAKRVITTFRTGTWDAYLNDHLKQRREVAKTVFCLVLVFALCWLPLHLARILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCANPIALYLVSKRFKNAFKSALCC         
         :                                                                                                                          
 5glh(A) : PNRAKRVITTFRTGTWDAYLNDHLKQRREVAKTVFCLVLVFALCWLPLHLARILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCANPIALYLVSKRFKNAFKSAL**         
           _____________1159_______________________________________________________________________________________________         

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		14.8
Translation
(A) 		0.2
Closure
(%) 		97.9
Bending Residues
( green ) 		  300 - 301
  1009 - 1022
  1033 - 1034
  1116 - 330
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

PyMOL Script

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