Extracellular Calcium-Sensing Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-542   SER-543  12.2 12.1 -11.5 30.9 63.3 72.2 -66.7
 SER-543   ARG-544  8.8 8.4 -22.8 8.6 47.3 34.6 152.7
 ARG-544   ASP-545  7.3 7.1 -36.5 -0.4 110.5 107.3 -12.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-546   LEU-547  4.1 3.3 42.5 17.9 48.2 64.6 308.8
 LEU-547   ALA-548  5.0 3.9 -22.4 -1.1 68.9 67.8 -10.9
 ALA-548   GLY-549  8.2 7.4 15.0 13.2 120.9 105.4 -97.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-550   ARG-551  5.7 5.7 24.3 -17.2 47.2 49.7 92.3
 ARG-551   LYS-552  5.3 5.5 -31.7 -45.0 112.1 122.5 -260.4
 LYS-552   GLY-553  3.2 3.6 -46.1 -6.9 139.5 151.0 -414.0
 GLY-553   ILE-554  0.4 4.1 -128.3 -29.3 116.1 136.1 963.4
 ILE-554   ILE-555  2.5 0.8 -15.8 -18.5 83.5 99.5 92.4
 ILE-555   GLU-556  5.8 3.4 -11.6 -21.6 152.0 133.7 -236.2
 GLU-556   GLY-557  7.2 5.0 -80.8 -2.2 93.8 123.2 -192.1
 GLY-557   GLU-558  10.1 7.0 -14.4 49.3 45.8 59.7 -139.7
 GLU-558   PRO-559  10.4 9.2 15.2 11.5 86.4 86.8 59.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-562   PHE-563  8.8 8.7 3.1 -6.2 74.6 75.9 23.7
 PHE-563   GLU-564  5.0 5.0 11.7 -28.8 131.2 132.6 91.0
 GLU-564   CYS-565  2.8 2.5 -0.6 -15.2 66.0 70.4 19.4
 CYS-565   VAL-566  0.5 1.1 6.5 -12.1 95.0 88.6 49.8
 CYS-565   VAL-566  0.5 1.1 6.5 -12.1 95.0 88.6 49.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-565   VAL-566  0.5 1.1 6.5 -12.1 95.0 88.6 49.8
 CYS-565   VAL-566  0.5 1.1 6.5 -12.1 95.0 88.6 49.8
 VAL-566   GLU-567  4.1 4.9 12.6 -2.7 62.7 68.3 61.1
 GLU-567   CYS-568  7.1 7.7 -16.2 1.4 47.8 48.1 77.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-572   TYR-573  15.1 15.2 -26.2 2.0 36.9 38.2 140.5
 TYR-573   SER-574  13.6 13.5 -17.8 39.6 106.2 97.0 -69.0
 SER-574   ASP-575  12.1 11.6 -22.4 7.6 25.8 26.4 93.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-582   ASN-583  11.4 11.8 10.1 7.0 113.2 113.4 -43.9
 ASN-583   LYS-584  15.1 15.5 19.5 9.9 79.3 77.4 0.9
 LYS-584   CYS-585  17.5 17.9 30.5 12.7 69.6 35.6 145.1
 CYS-585   PRO-586  20.2 19.7 -1.3 9.9 74.5 75.0 -67.2
 PRO-586   ASP-587  23.7 23.4 -36.8 -6.0 117.4 88.5 -62.8
 ASP-587   ASP-588  26.4 26.0 0.0 4.4 23.8 30.0 48.1
 ASP-588   PHE-589  27.8 27.8 -19.0 13.2 127.9 133.7 -25.5
 PHE-589   TRP-590  24.3 24.3 -9.1 32.4 80.0 61.5 -64.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees