Piezo-Type Mechanosensitive Ion Channel Component 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ALA-1326   ASN-1327  25.5 24.1 -0.1 0.4 76.9 74.3 8.9
 ASN-1327   LEU-1328  22.2 21.2 -2.1 0.2 75.0 78.6 15.6
 LEU-1328   LYS-1329  23.8 23.7 -0.7 0.3 143.3 150.0 -2.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 VAL-1498   LEU-1499  23.9 23.6 -3.0 1.6 138.3 132.4 -5.6
 LEU-1499   SER-1500  26.9 27.0 0.2 0.5 54.6 43.9 4.8
 SER-1500   THR-1501  24.9 25.4 7.1 2.3 50.2 50.7 23.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LEU-1708   VAL-1709  21.9 22.2 -2.0 -7.5 46.3 41.5 52.8
 VAL-1709   LEU-1710  20.7 20.7 -17.7 22.7 103.2 88.1 8.2
 LEU-1710   PRO-1711  19.9 20.2 6.5 -1.8 55.7 57.2 37.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 VAL-1714   PHE-1715  14.5 15.9 10.6 15.4 97.4 118.1 -36.7
 PHE-1715   LEU-1716  11.3 12.8 -29.2 51.3 144.0 133.7 51.8
 LEU-1716   TRP-1717  10.2 10.4 -23.3 55.9 128.5 122.7 57.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASP-1975   VAL-1976  7.7 11.4 2.6 -3.0 47.9 16.7 -9.3
 VAL-1976   TYR-1977  4.6 9.3 52.0 2.8 80.6 88.5 19.9
 TYR-1977   ALA-1978  3.4 7.0 -0.1 -5.5 157.0 149.0 5.4
 ALA-1978   LEU-1979  3.0 6.3 7.4 6.2 82.5 80.0 21.9
 LEU-1979   MET-1980  1.4 4.8 -0.4 -3.5 59.7 60.1 0.6
 MET-1980   PHE-1981  1.9 2.2 2.9 -0.5 59.0 60.6 0.0
 PHE-1981   LEU-1982  4.0 2.9 -4.1 -3.9 144.8 145.4 -22.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LEU-2037   TYR-2038  8.7 7.8 1.0 6.0 65.9 65.5 9.9
 TYR-2038   LEU-2039  8.0 8.7 -5.2 -8.8 89.4 77.1 -5.8
 LEU-2039   ARG-2040  11.8 12.3 2.3 -25.8 156.3 165.5 75.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASN-2076   ALA-2077  25.3 24.2 -6.4 -60.7 86.7 93.3 -3.4
 ALA-2077   VAL-2078  23.2 21.4 0.8 -7.2 88.8 101.5 -22.1
 VAL-2078   ALA-2079  20.8 18.7 0.4 1.1 17.6 35.7 -7.5
 ALA-2079   GLN-2080  20.9 18.3 3.3 1.3 106.0 121.9 1.8
 ALA-2079   GLN-2080  20.9 18.3 3.3 1.3 106.0 121.9 1.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ALA-2079   GLN-2080  20.9 18.3 3.3 1.3 106.0 121.9 1.8
 ALA-2079   GLN-2080  20.9 18.3 3.3 1.3 106.0 121.9 1.8
 GLN-2080   LEU-2081  20.4 18.2 8.1 5.1 68.1 63.6 5.1
 LEU-2081   TRP-2082  17.5 15.8 -4.1 -1.8 63.0 67.0 -5.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 TYR-2095   GLN-2096  6.6 8.4 -0.6 0.3 96.0 87.4 9.4
 GLN-2096   ILE-2097  4.4 7.1 4.9 3.6 16.3 24.9 14.4
 ILE-2097   ARG-2098  3.5 5.8 3.5 3.2 64.4 61.2 13.4
 ARG-2098   CYS-2099  7.0 9.1 -1.8 4.7 75.0 75.5 9.8
 CYS-2099   GLY-2100  8.9 11.1 0.6 -34.5 72.5 72.5 -35.5
 GLY-2100   TYR-2101  7.8 9.7 75.8 123.5 139.3 127.0 387.5
 TYR-2101   PRO-2102  8.9 13.0 -94.3 27.4 85.1 36.7 -508.5
 PRO-2102   THR-2103  12.3 12.0 161.8 21.9 98.0 101.9 54.7
 THR-2103   ARG-2104  15.1 15.6 146.9 -138.0 171.1 131.9 -31.3
 ARG-2104   ILE-2105  16.1 17.0 57.5 -47.2 118.9 143.0 -34.5
 ILE-2105   LEU-2106  12.9 15.8 -169.4 -100.6 41.0 38.9 -237.2
 LEU-2106   GLY-2107  14.9 16.6 11.6 -177.8 153.8 127.6 483.0
 GLY-2107   ASN-2108  14.8 14.5 17.6 3.9 116.2 88.1 -17.8
 ASN-2108   PHE-2109  12.2 11.7 -19.1 13.5 74.5 48.7 11.7
 PHE-2109   LEU-2110  10.0 13.9 -20.0 27.5 12.2 43.7 -6.9
 LEU-2110   THR-2111  10.3 11.1 -35.2 37.3 69.7 47.9 -18.9
 THR-2111   LYS-2112  14.1 10.5 -69.2 14.6 113.0 70.7 -3.3
 LYS-2112   LYS-2113  15.0 14.4 31.4 49.1 139.2 128.0 -177.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees